Tag: M.W=100-150

Safety of 1,3-Dimethoxybenzene. In 2019 ORG LETT published article about REDOX-ACTIVE ESTERS; RING-OPENING TRIFLUOROMETHYLATION; BOND-FORMING REACTIONS; ZINC-HOMOENOLATE; C-C; KETONES; ALPHA in [Mills, L. Reginald; Zhou, Cuihan; Fung, Emily; Rousseaux, Sophie A. L.] Univ Toronto, Dept Chem, Davenport Res Labs, 80 St George St, Toronto, ON M5S 3H6, Canada; [Zhou, Cuihan] McGill Univ, Dept Chem, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada in 2019, Cited 35. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

Metal homoenolates are valuable synthetic intermediates which provide access to beta-functionalized ketones. In this report, we disclose a Ni-catalyzed beta-alkylation reaction of cyclopropanol-derived homoenolates using redox-active N-hydroxyphthalimide (NHPI) esters as the alkylating reagents. The reaction is compatible with 1 degrees, 2 degrees, and 3 degrees NHPI esters. Mechanistic studies imply radical activation of the NHPI ester and 2e beta-carbon elimination occurring on the cyclopropanol.

Safety of 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Mills, LR; Zhou, CH; Fung, E; Rousseaux, SAL or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Name: 3-Methylbenzoic acid. Authors Singh, A; Farooqui, M; Diwan, MF; Pardeshi, RK in INT JOURNAL PHARMACEUTICAL SCIENCES & RESEARCH published article about in [Singh, Anantkumar; Farooqui, Mazahar; Diwan, Mohammed Furqan] Dr Rafiq Zakaria Coll Women, Aurangabad 431001, Maharashtra, India; [Pardeshi, R. K.] St Ramdas Coll, Jalna 431209, Maharashtra, India in 2020.0, Cited 14.0. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

A number of N-(5-p-tolyl-1,3,4-thiadiazole-2-yl) benzamide derivatives were synthesized from aromatic acid. The antibacterial activity of these newly synthesized N-(5-p-tolyl-1,3,4-thiadiazole-2-yl) benzamide derivatives against Gram-positive bacteria and Gram-negative bacteria was also studied using the minimum inhibition concentration method. The synthesized compounds were showed better results for antibacterial evaluation against gram-positive (Staphylococcus aureus, Bacillus subtilis), gram-negative (Escherichia coli, Pseudomonas aeruginosa) and fungal strains (Candida albicans, A. niger) and were found to be good antibacterial and antifungal agents. Most of the derivatives showed significant antibacterial and antifungal activity against standard. Compared to other methods, the advantageous features of this methodology are operational simplicity, including excellent yields and short reaction time. The developed synthetic protocol represents a very simple and easy to handle for the synthesis of substituted N-(5-p-tolyl-1,3,4-thiadiazole-2-yl) benzamide derivatives.

Name: 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Singh, A; Farooqui, M; Diwan, MF; Pardeshi, RK or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recommanded Product: 3-Methylbenzoic acid. Recently I am researching about CARBOXYLIC-ACIDS; BOND FUNCTIONALIZATIONS; OXIDASE CATALYSIS; ALKENYLATIONS; DEHYDROGENATION; ISOPESTACIN; STRATEGY; WATER, Saw an article supported by the Natural Science Foundation of Shandong Province, ChinaNatural Science Foundation of Shandong Province [ZR2016JL009]; University of Jinan. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Wang, R; Xu, HY; Li, TT; Zhang, Y; Wang, SF; Chen, GZ; Li, CC; Zhao, HQ. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid

A catalytic annulation cascade is achieved that affords an efficient access to phthalides from readily available benzoic acids and saturated ketones. The reaction is catalyzed by a bimetallic Ir/Cu system and proceeds via the combination of Cu-catalyzed dehydrogenation of ketones and Ir-catalyzed direct C-H functionalization under the assistance of the weakly coordinating carboxyl followed by the beta-H elimination and intramolecular Michael addition. This method shows a broad scope of substrates and good functional group tolerance. The protocol furnishes an alternative strategy for the construction of diverse 3-substituted phthalides.

Recommanded Product: 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Wang, R; Xu, HY; Li, TT; Zhang, Y; Wang, SF; Chen, GZ; Li, CC; Zhao, HQ or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Recently I am researching about METAL-FREE SYNTHESIS; CARBOXYLIC-ACIDS; 2+2 PHOTOCYCLOADDITION; PHOTOREDOX CATALYSIS; ESTERS; TRIFLUOROMETHYLATION; ACTIVATION; COMPLEXES; ARYLATION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21771131, 21471108, 21773163]; Natural Science Foundation of Jiangsu ProvinceNatural Science Foundation of Jiangsu Province [BK20161276]; Scientific and Technologic Infrastructure of Suzhou [SZS201708]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Zhu, DL; Li, HX; Xu, ZM; Li, HY; Young, DJ; Lang, JP. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid. Formula: C8H8O2

We report an approach to the visible light-initiated, nickel-catalyzed esterification of carboxylic acids with aryl bromides. Thioxanthen-9-one works as a triplet photosensitizer to significantly accelerate this cross-coupling to provide aryl esters in moderate to excellent yields at room temperature. A mechanistic investigation indicates that this esterification undergoes the stepwise oxidative addition of an arylbromide to nickel, transmetalation of an aryl-Ni(ii) bromide complex, energy transfer from thioxanthen-9-one to an excited-state aryl-Ni(ii) carboxylate and reductive elimination to the aryl ester. This study contributes to the utilization of ketones as triplet photosensitisers in photochemical transformations.

Formula: C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact Zhu, DL; Li, HX; Xu, ZM; Li, HY; Young, DJ; Lang, JP or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Name: 1,3-Dimethoxybenzene. Authors Ojah, EO; Moronkola, DO; Ajiboye, CO; Yusuf, TL; Adeniyi-Akee, MA in TAYLOR & FRANCIS LTD published article about in [Ojah, Emmanuel Onah; Moronkola, Dorcas Olufunke; Ajiboye, Clement Odunayo] Univ Ibadan, Dept Chem, Ibadan, Nigeria; [Ojah, Emmanuel Onah] Mt Top Univ, Dept Chem Sci, Coll Basic & Appl Sci, Makogi Oba, Ogun State, Nigeria; [Yusuf, Tunde Lewis] Univ KwaZulu Natal, Sch Chem & Phys, Private Bag X54001,Westville Campus, ZA-4000 Durban, South Africa; [Adeniyi-Akee, Mukaram Akintunde] Igbined Univ, Dept Pharmaceut Chem, Coll Pharm, Okada, Edo State, Nigeria in 2021, Cited 47. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

The chemical composition of essential oils (EOs) isolated by hydrodistillation from Pterocarpus soyauxii Taub. root wood and root bark were determined for the first time by GC/MS analysis. The EOs gave a percentage yield (w/w) of 0.34 % and 0.31 % for root wood and root bark respectively. A total of 60 compounds accounting for 86.1 % of the root wood EO composition were identified with monoterpenes (45.4 %) and sesquiterpenes (14.7 %) as predominant constituents. Root bark EO gave 53 identified constituents which make up about 78.5 % of the EO dominated by non-terpenes (23.4 %) and alkanes (14.1 %). The EOs are good sources of limonene (16.9 %), gamma-terpinene (9.8 %) and p-cymene (6.70 %). The anti-diabetic (alpha-amylase and alpha-glucosidase models) and antioxidant activities (DPPH and H2O2 models) of EOs were evaluated in comparison with standard drugs. Alpha-amylase inhibition gave IC50 values (mg/mL) of 0.0493 and 0.0471 for root wood and root bark EOs respectively, compared to acarbose the standard anti-diabetic drug (0.0401) while alpha-glucosidase assay gave IC50 values (mg/mL) of 0.0517 and 0.0486 for root wood and root bark EOs respectively, compared with acarbose (0.0418). In the DPPH antioxidant assay, root bark EO showed higher activity (0.157 mg/mL) compared to root wood EO (0.159 mg/mL) while Root wood and root bark EOs had IC(50 )values (mg/mL) of 0.157 and 0.171 respectively using the H2O2 model. Results revealed the presence of chemical constituents in the EOs which could be responsible for activities expressed by the plant.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Ojah, EO; Moronkola, DO; Ajiboye, CO; Yusuf, TL; Adeniyi-Akee, MA or concate me.. Name: 1,3-Dimethoxybenzene

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Name: 1,3-Dimethoxybenzene. In 2020 GREEN CHEM published article about FUNCTIONALIZATION; METAL; IDENTIFICATION; THIOCYANATION in [Wu, Yaxing; Ding, Hongliang; Zhao, Ming; Ni, Zhong-Hai; Cao, Jing-Pei] China Univ Min & Technol, Minist Educ, Key Lab Coal Proc & Efficient Utilizat, Xuzhou 221116, Jiangsu, Peoples R China in 2020, Cited 50. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.

The electrochemical-induced C-H methylthiolation of electron-rich aromatics has been accomplished via a three component cross-coupling strategy. Potassium thiocyanate (KSCN) as both the supporting electrolyte and sulfur source and methanol as the methylation reagent are used. This protocol is versatile for various (hetero)aromatic compounds such as aniline, anisole and indole. The reaction proceeds under mild conditions without any metal catalyst, exogenous oxidant and highly toxic sulfur reagent. Importantly, such an electrochemical-induced methylthiolated reaction could be easily scaled up with good efficiency.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Wu, YX; Ding, HL; Zhao, M; Ni, ZH; Cao, JP or concate me.. Name: 1,3-Dimethoxybenzene

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Direct Amidation of Carboxylic Acids with Nitroarenes WOS:000494562600063 published article about PEPTIDE COUPLING REAGENTS; SECONDARY AMIDES; CADOGAN REACTION; TRANSAMIDATION; ARYL; INHIBITORS; CHEMISTRY; AMINES; AMINOCARBONYLATION; HYDROAMINATION in [Cheung, Chi Wai; Ma, Jun-An] Tianjin Univ, Tianjin Key Lab Mol Optoelect Sci, Dept Chem, Tianjin 300072, Peoples R China; Tianjin Univ, Tianjin Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China; Joint Sch NUS & TJU, Int Campus Tianjin Univ, Fuzhou 350207, Fujian, Peoples R China in 2019, Cited 87. Safety of 3-Methylbenzoic acid. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7

N-Aryl amides are an important class of compounds in pharmaceutical and agrochemical chemistry. Rapid and low-cost synthesis of N-aryl amides remains in high demand. Herein, we disclose an operationally simple process to access N-aryl amides directly from readily available nitroarenes and carboxylic acids as coupling substrates. This method involves the in situ activation of carboxylic acids to acyloxyphosphonium salt for one-pot amidation, without the need for isolation of the corresponding synthetic intermediates. Furthermore, the ease of preparation and workup allow the quick and efficient synthesis of a wide range of N-aryl amides, including several amide-based druglike and agrochemical molecules.

Safety of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Wang, SP; Cheung, CW; Ma, JA or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Authors Bomon, J; Bal, M; Achar, TK; Sergeyev, S; Wu, X; Wambacq, B; Lemiere, F; Sels, BF; Maes, BUW in ROYAL SOC CHEMISTRY published article about in [Bomon, Jeroen; Bal, Mathias; Achar, Tapas Kumar; Sergeyev, Sergey; Lemiere, Filip; Maes, Bert U. W.] Univ Antwerp, Dept Chem, Groenenborgerlaan 171, B-2020 Antwerp, Belgium; [Wu, Xian; Wambacq, Ben; Sels, Bert F.] Katholieke Univ Leuven, Ctr Sustainable Catalysis & Engn, Celestijnenlaan 200F, B-3001 Leuven, Belgium in 2021, Cited 104. Recommanded Product: 151-10-0. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0

A green, efficient and cheap demethylation reaction of aromatic methyl ethers with mineral acid (HCl or H2SO4) as a catalyst in high temperature pressurized water provided the corresponding aromatic alcohols (phenols, catechols, pyrogallols) in high yield. 4-Propylguaiacol was chosen as a model, given the various applications of the 4-propylcatechol reaction product. This demethylation reaction could be easily scaled and biorenewable 4-propylguaiacol from wood and clove oil could also be applied as a feedstock. Greenness of the developed method versus state-of-the-art demethylation reactions was assessed by performing a quantitative and qualitative Green Metrics analysis. Versatility of the method was shown on a variety of aromatic methyl ethers containing (biorenewable) substrates, yielding up to 99% of the corresponding aromatic alcohols, in most cases just requiring simple extraction as work-up.

Recommanded Product: 151-10-0. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Bomon, J; Bal, M; Achar, TK; Sergeyev, S; Wu, X; Wambacq, B; Lemiere, F; Sels, BF; Maes, BUW or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Safety of 3-Methylbenzoic acid. Recently I am researching about EQUILIBRIUM-CONSTANTS; AROMATIC-ACIDS; URANIUM(VI); CRYSTAL; ION; BENZOATE; MODEL; EXAFS, Saw an article supported by the Nuclear R&D Program of the National Research Foundation of Korea – Korean Ministry of Science and ICT [2016M2B2B1945252, 2017M2A8A5014801]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Choi, S; Yun, JI. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid

Aqueous complexation of uranyl(VI) ions with methoxy- and methylbenzoates in 0.1 M NaClO4 solutions was studied by means of UV-vis absorption and Raman spectroscopy. The predominance of 1:1 complexation (uranyl to ligand) was verified for all uranyl carboxylates under acidic conditions (-log [H+] < 3.2), and absorption spectra, stability constants, and symmetric stretching frequencies of the uranyl group of the complexes were determined for the first time. For meta- and parasubstituted benzoates, a linear free energy relationship (LFER) was observed between the equilibrium constants for the protonation (log beta(p)) and uranyl complexation (log beta(U)) reactions, and the electronic effects of the substituents were successfully described by the Hammett equation. In the case of ortho-substituted benzoates, the stability constant of uranyl 2-methoxybenzoate is slightly lower than the LFER trend, which is generally explained by the destabilization of cross-conjugation in the uranyl complex due to the steric hindrance between the reaction center and adjacent methoxy group. On the contrary, the stability constant of uranyl 2-methylbenzoate is comparable to the LFER trend, implying that the steric effect is relatively insignificant for the smaller methyl group. The utility of such thermodynamic correlations between the uranyl-substituted benzoates is useful for the molecular understanding and predictive modeling of chemical interactions between actinyl(VI) ions and various organic carboxyl groups. Safety of 3-Methylbenzoic acid. About 3-Methylbenzoic acid, If you have any questions, you can contact Choi, S; Yun, JI or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

SDS of cas: 151-10-0. I found the field of Chemistry; Food Science & Technology; Nutrition & Dietetics very interesting. Saw the article Synthesis and evaluation of aromatic methoxime derivatives against five postharvest phytopathogenic fungi of fruits. Main structure-activity relationships published in 2020, Reprint Addresses Kaufman, TS; Bracca, ABJ (corresponding author), Univ Nacl Rosario, CONICET, Inst Quim Rosario, IQUIR,UNR, Suipacha 531, RA-2000 Rosario, Argentina.; Kaufman, TS; Bracca, ABJ (corresponding author), Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, Suipacha 531, RA-2000 Rosario, Argentina.; Derita, MG (corresponding author), Univ Nacl Rosario, Fac Ciencias Bioquim & Farmaceut, Farmacognosia, Suipacha 531,S2002LRK, Rosario, Argentina.; Derita, MG (corresponding author), Univ Nacl Litoral, Inst Ciencias Agr Litoral ICiAgro Litoral, CONICET, Kreder 2805, RA-3080 Esperanza, Argentina.. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene.

The antifungal activity of a library of twenty-four aromatic methoximes was examined against five representative postharvest phytopathogenic fungi. The panel included Penicillium digitatum, Penicillium italicum, Rhizopus stolonifer, Botrytis cinerea and Monilinia fructicola, all of which cause relevant economic losses worldwide as a result of affecting harvested fruits. The minimum inhibitory concentrations and minimum fungicidal concentrations of each compound were defined and the main structure-activity relationships were determined. Although other congeners were more potent, drug likeliness considerations pointed to the methoxime derived from 2,4-dihydroxypropiophenone as the compound with the most suitable profile. The morphology of the colonies of the fungal strains treated with the methoxime was examined microscopically and the compound was also tested in freshly harvested peaches and oranges, exhibiting promising control profiles in both fruits, similar to those of the commercial agents Imazalil and Carbendazim.

About 1,3-Dimethoxybenzene, If you have any questions, you can contact Cortes, I; di Liberto, MG; Kaufman, TS; Derita, MG; Bracca, ABJ or concate me.. SDS of cas: 151-10-0

Reference:
Isothiazole – Wikipedia,
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