Tag: 100-200

On November 1, 2015, De, Bibekananda; Gupta, Kuldeep; Mandal, Manabendra; Karak, Niranjan published an article.Recommanded Product: 26172-54-3 The title of the article was Biocide immobilized OMMT-carbon dot reduced Cu2O nanohybrid/hyperbranched epoxy nanocomposites: Mechanical, thermal, antimicrobial and optical properties. And the article contained the following:

The present work demonstrated a transparent thermosetting nanocomposite with antimicrobial and photoluminescence attributes. The nanocomposites are fabricated by incorporation of different weight% (1, 2 and 3) of a biocide immobilized OMMT-carbon dot reduced Cu2O nanohybrid (MITH-NH) in the hyperbranched epoxy matrix. MITH-NH is obtained by immobilization of 2-methyl-4-isothiazolin-3-one hydrochloride (MITH) at room temperature using sonication on OMMT-carbon dot reduced Cu2O nanohybrid. The nanohybrid is prepared by reduction of cupric acetate using carbon dot as the reducing agent in the presence of OMMT at 70°. The significant improvements in tensile strength (∼ 2 fold), elongation at break (3 fold), toughness (4 fold) and initial thermal degradation temperature (30°) of the pristine hyperbranched epoxy system are achieved by incorporation of 3 weight% of MITH-NH in it. The nanocomposites exhibit strong antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae and Pseudomonas aeruginosa bacteria and Candida albicans, a fungus. The nanocomposite also shows significant activity against biofilm formation compared to the pristine thermoset. Further, the nanocomposite films emit different colors on exposure of different wavelengths of UV light. The properties of these nanocomposites are also compared with the same nanohybrid without OMMT. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Recommanded Product: 26172-54-3

The Article related to epoxy resin copper oxide ommt nanocomposite thermal mech property, antimicrobial activity, biocide immobilization, carbon dot reduced cu(2)o-ommt nanohybrid, hyperbranched epoxy nanocomposite, mechanical, optical property and other aspects.Recommanded Product: 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On April 12, 2007, Kyriatsoulis, Apostolos; Feldmann, Susanne; Huber, Erasmus; Kobold, Uwe; Puhlmann, Angela; Von Proff, Leopold; Waechter, Nicole published a patent.Synthetic Route of 26172-54-3 The title of the patent was Release reagent for vitamin D compounds. And the patent contained the following:

The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analyzed, the use of the reagent to release vitamin D compounds, as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunol. reagents. 25-Hydroxyvitamin D3-3-hemisuccinate-keyhole hemocyanin conjugates were prepared and used to generate antibodies in sheep. An affinity chromatog. stationary phase was prepared to purify the antibodies. Immunoassay reagents were prepared and used to determine 25-hydroxyvitamin D in serum samples from humans of Caucasian descent and of African descent. When release reagent contained 10 % DMSO, DMF, or N-methylpyrrolidone, the values from the immunoassay correlated very well with values from LC-MS-MS and were independent of the phenotype of the vitamin D-binding protein. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Synthetic Route of 26172-54-3

The Article related to reagent releasing binding protein vitamin d compound assay, dmso release reagent hydroxyvitamin d immunoassay blood serum, dmf release reagent hydroxyvitamin d immunoassay blood serum, n methylpyrrolidone release reagent hydroxyvitamin d immunoassay blood serum, caucassian african human hydroxyvitamin d release reagent immunoassay and other aspects.Synthetic Route of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On August 8, 1978, Lewis, Sheldon N.; Miller, George A.; Law, Andrew B. published a patent.Formula: C4H6ClNOS The title of the patent was 3-Isothiazolones as biocides. And the patent contained the following:

Isothiazolones I (R, R1 = H, halogen, C1-4 alkyl; R2 = optionally substituted C1-18 alkyl, alkenyl, alkynyl, cycloalkyl, aralkyl, aryl) (106 compounds) were prepared Thus 79 g (SCH2CH2CONHMe)2 was cyclized in the presence of SO2Cl2 to give 11.5 g I (R = H, R1 = Cl, R2 = Me). I have bactericidal, fungicidal, and algicidal activity. Their use in lubricating oils, cooling water, paints, polymer emulsions, laundry detergents, soaps, cosmetics, paper, leather, textiles, and wood products is illustrated. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Formula: C4H6ClNOS

The Article related to algicides, coating materials, cosmetics and personal care products, detergents, drinking waters, fungicides, leather, lubricating oils, paper, polymers role: uses (uses), soaps role: rct (reactant), ract (reactant or reagent), textiles, wood preservatives and other aspects.Formula: C4H6ClNOS

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On June 30, 1988, Lindner, Wolfgang published a patent.Category: isothiazole The title of the patent was Process for isolation of isothiazolinone derivatives using strong acids. And the patent contained the following:

Isothiazolinone compounds I (R = C1-3 alkyl; X = halogen; or R = C1-16 alkyl, C5-6 cycloalkyl; X = H) are isolated from tech. mixtures containing ≥1 I compound and/or 4-halo-2-alkyl-3-isothiazolinone and/or 4,5-dihalo-2-alkyl-3-isothiazolinones and/or their halogen addition compounds and/or nitroso compounds, by dissolving the wet mixture in an organic solvent which is slightly miscible or immiscible with water, drying the organic solution, treating with a strong acid, recovering the precipitated I salt, and hydrolyzing it if desired. A 100 g portion of an aqueous tech. solution containing 2-methyl-3-isothiazolinone(II) 4.41, 5-chloro-2-methyl-3-isothiazolinone(III) 10.27, and 4,5-dichloro-2-methyl-3-isothiazolinone (IV) ≈0.3%, was mixed with 100 g AcOEt, the organic layer separated, dried over Na2SO4, the organic solution saturated with HCl, the precipitated salts separated by filtration, and dissolved with stirring in the aqueous phase to give a formulation containing II 4.35, III 9.96, and IV <0.01 g. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Category: isothiazole

The Article related to isothiazolinone derivative isolation process, polychloroisothiazolinone separation isothiazolinone purification, acid isothiazolinone purification, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Category: isothiazole

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On November 27, 2020, Zeng, Xiangxi published a patent.Safety of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Preparation of high washing fastness bronzing pulp. And the patent contained the following:

Title bronzing pulp is prepared from (a) 45-60 parts of ethylene-vinyl acetate copolymer emulsion, (b) 10-20 parts of styrene-acrylic emulsion, (c) 0.5-2 parts of odorless kerosene, (d) 5-8 parts of microsphere foaming powder, (e) 2-6 parts of fatty alc. polyoxyethylene ether, (f) 4-6 parts of hot melt powder, (g) 0.02-0.1 part of preservative, and (h) 1-5 parts of water; the preservative is a compound of 5-chloro-2-methylisothiazolin-3-one hydrochloride and 2-methyl-4-isothiazolin-3-one hydrochloride; and the solid content of the ethylene-vinyl acetate copolymer emulsion is 52-55% and the solid content of the styrene-acrylic emulsion is 45-55%. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Safety of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to washing fastness bronzing pulp ethylene vinyl acetate copolymer emulsion, Coatings, Inks, and Related Products: Acrylic and Water-Sol (Electrophoretic) Resin Coatings and other aspects.Safety of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On December 13, 1977, Weiler, Ernest D.; Miller, George A. published a patent.COA of Formula: C4H6ClNOS The title of the patent was Halogenated 3-isothiazolidinone 1-oxide and 1,1-dioxides. And the patent contained the following:

The title compounds I (R1 = H, C1-18 unsubstituted alkyl, HO, halo, C1-4 carbalkoxy, cyano or carboxy-monosubstituted C1-18 alkyl, C3-8 cycloalkyl, PhCH2, halo C1-4 alkyl, C1-4 alkoxy, nitro or cyano-substituted benzyl, Ph, naphthyl, nitro-substituted Ph or naphthyl; R1, R2 = H, halo; R3 = halo; n = 0, 1) were prepared by halogenation of the corresponding 4-isothiazolin-3-one. Thus, 4-isothiazolin-3-one 1-oxide was brominated with Br to give I (R = R1 = R2 = H, R3 = Br, n = 1) (II). II was fungicidal at 500 ppm, bactericidal at 123 ppm and at 10 lbs/acre controlled monocotyledons by 72%. At 150 ppm II controlled rice blast by 70-89%. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).COA of Formula: C4H6ClNOS

The Article related to bactericide haloisothiazolidinone oxide, fungicide isothiazolidinone oxide, herbicide isothiazolidinone oxide, algicide isothiazolidinone oxide, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.COA of Formula: C4H6ClNOS

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On October 2, 1979, Weiler, Ernest D. published a patent.Quality Control of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Isothiazolidin-3-ones. And the patent contained the following:

Isothiazolidinones I (R = H, optionally substituted C1-18 alkyl, phenylalkyl, Ph, naphthyl, cycloalkyl; R1, R3 = halogen, alkyl; R2 = halogen) were prepared Thus 2,4-dimethyl-3-isothiazolinone was chlorinated with Cl to give 68% I (R = R1 = Me, R2 = R3 = Cl), which had a min. inhibitory concentration of 125 ppm against Escherichia coli, Staphylococcus aureus, Aspergillus niger, and Rhizopus stolonifer. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Quality Control of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to haloisothiazolidinone, bactericide haloisothiazolidinone, fungicide haloisothiazolidinone, isothiazolinone halogenation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Quality Control of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On July 28, 1998, Onishi, Toshimasa; Morita, Takashi; Yamamoto, Yoshi; Tojo, Tamaki; Tanaka, Ikuya published a patent.COA of Formula: C4H6ClNOS The title of the patent was Preparation of 3-isothiazolones as microbicides. And the patent contained the following:

Title compounds I [X, Z = H, halo, C1-4 alkyl; Y = C1-8 alkyl, C5-6 cycloalkyl, C≤8 aralkyl, C6 aryl, (substituted) aryl], useful as microbicides (no data), not containing alkali metal salts and H2O produced in neutralization are prepared by neutralization of I hydrohalides with alkali metal bases in organic solvents having solubility of I and no solubility of alkali metal salts in the presence of small amount of H2O, dehydration of the reaction mixtures, and removal of alkali metal salts by solid-liquid separation, recovery of I. 3-Isothiazolone hydrochloride AcOEt solution (5-chloro-2-methyl-4-isothiazolin-3-one (II)/2-methyl-4-isothiazolin-3-one (III) ratio of 4.4/1) was treated with NaHCO3 in the presence of H2O at room temperature for 1 h, dried, separation of a solid from the reaction mixture, and distilled to give 85% 3-isothiazolone with II/III ratio of 4.8/1 containing ≤0.1% H2O and NaCl. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).COA of Formula: C4H6ClNOS

The Article related to isothiazolone preparation purification microbicide, neutralization isothiazolone hydrohalide alkali metal base, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.COA of Formula: C4H6ClNOS

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On January 19, 1999, Kim, Sang-Hwan; Park, Jong-Ho; Kim, Jin-Mae; Choi, Ki-Sung; Chow, Myang-Ho; Han, Seung-Jon published a patent.Electric Literature of 26172-54-3 The title of the patent was Preparation of anhydrous isothiazolones as microbicides. And the patent contained the following:

Anhydrous isothiazolones, useful as microbicides (no data), are prepared by extraction from solutions using halo hydrocarbons or nitro hydrocarbons and removal of the halo or nitro hydrocarbons from the extracts An aqueous solution containing ∼3:1 5-chloro-2-methyl-3-isothiazolone.HCl and 2-methyl-3-isothiazolone.HCl was mixed with CH2Cl2 and then the organic layer was evaporated and dissolved into ethylene glycol to give a solution showing H2O content 500 ppm (H2O content of ethylene glycol 450 ppm) and complete storage stability at 65° for ≥16 days. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Electric Literature of 26172-54-3

The Article related to isothiazolone anhydrous preparation microbicide, extraction isothiazolone halo nitro hydrocarbon, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Electric Literature of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On July 17, 1991, Petigara, Ramesh Balubhai; Woodruff, Robert Alva; Pendell, Barry Jack; Leister, Norman Andrew published a patent.COA of Formula: C4H6ClNOS The title of the patent was Preparation of salt- and water-free 3-isothiazolones. And the patent contained the following:

The title compounds [I; X = H, alkyl; X1 = H, Cl, alkyl; Y = (un)substituted alkyl] were prepared by neutralization of Im.HmZ (Z = Cl, Br, SO4, FSO3; m = 1, 2) with anhydrous NH3 in an organic solvent. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).COA of Formula: C4H6ClNOS

The Article related to isothiazolone anhydrous base preparation, ammonia neutralization isothiazolone acid salt, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.COA of Formula: C4H6ClNOS

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com