Tag: 100-200

On June 20, 2017, Bao, Xingyan; Luo, Weixiao; Tan, Baiqing; Li, Zhiming published a patent.Reference of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Reagent for detecting glucose by hexokinase method with high stability and low cost. And the patent contained the following:

The present invention relates to the field of detection technol. for detecting blood GLU by hexokinase method, and provides liquid dual reagent composed of reagent 1 and reagent 2. Reagent 1 mainly includes buffer solution, Mg2+, ionic equilibrium agent, preservative, NAD (oxidized coenzyme I), and protective agent, and surfactant, and reagent 2 includes buffer solution, protective agent, surfactant, preservative, hexokinase (HK), glucose-6-phosphate dehydrogenase (G6P-DH) and ATP-Na2. The invention targetedly adds various protective agents including polyethylene glycol, Tween-80 and FAD to ensure stability of enzymes in reagent, adds various surfactants in order to reduce cost, particularly usage of enzymes, and to improve emulsification to enzymes and use efficiency of enzymes, thus greatly reduces reagent cost, and is very convenient for application and promotion clin. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Reference of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to blood glucose hexokinase dehydrogenase blood diagnostic reagent, Biochemical Methods: Reagents and other aspects.Reference of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On January 22, 1992, Hoss, Gerhard; Pappert, Gunter; Schmidt, Axel published a patent.Safety of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Preservation of diagnostic test reagents and kits. And the patent contained the following:

Diagnostic test kits and the reagents therein are preserved from microbial degradation by a combination of ≥2 of 2-methyl-4-isothiazolin-3-one-HCl, 2-hydroxypyridine N-oxide, chloroacetamide, N,N-methylenebis[N-(1-hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea (I), and 5-bromo-5-nitro-1,3-dioxane. Thus, the reagents in a kit for automated determination of albumin (succinate buffer, pH 4.2; bromcresol green; Brij 35; and preservatives 2-hydroxypyridine N-oxide and I) were incubated with a mixture of bacteria, fungi, and yeasts for 6 wk at 23°. After this time, the bacterial count was reduced by 1.6 x 104 and the count of fungi and yeasts by 8.3 x 104. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Safety of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to preservative diagnostic reagent solution, Biochemical Methods: Reagents and other aspects.Safety of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On December 22, 2020, Gu, Zhenpeng; Yang, Zhaohui; Zhang, Xiaona; Zhao, Lin; Liu, Wei; Chen, Qi published a patent.SDS of cas: 26172-54-3 The title of the patent was Preparation of 2-methyl-4-isothiazolin-3-one (MIT) aqueous solution by using dipolar aprotic solvent. And the patent contained the following:

The title method includes (1) mixing 3,3′-dithiobis(N-methylpropionamide) or 3-mercapto-N-methylpropanamide with solvent, and adding halogenating agent (chlorine gas, sulfuryl chloride, etc.) for a halogenation ring-closing reaction. (2) Filtering to obtain a product, washing the filter cake with Et acetate, and drying to obtain 2-methyl-4-isothiazolin-3-one hydrochloride solid. (3) Dissolving with a sodium carbonate aqueous solution to obtain an aqueous solution having pH of 5.0-7.0 and the mass content of 2-methyl-4-isothiazolin-3-one of 50%. The solvent comprises chlorination solvent (dichloromethane, chloroform, etc.) and dipolar aprotic solvent (acetonitrile, DMF, etc.). The prepared 2-methyl-4-isothiazolin-3-one has the purity up to above 99.9% and the content of 5-chloro-2-methyl-4-isothiazolin-3-one controlled at below 100 ppm. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).SDS of cas: 26172-54-3

The Article related to methyl isothiazolinone preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.SDS of cas: 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On May 24, 2017, Li, Xiaobin; Wang, Jianguo; Wang, Xinhai; Liu, Liming published a patent.Computed Properties of 26172-54-3 The title of the patent was Preparation method of high-purity 2-alkyl-4-isothiazolin-3-one. And the patent contained the following:

A process for preparation of high-purity 2-alkyl-4-isothiazolin-3-one is disclosed. The process comprises reaction of N,N’-dimethyl-3,3′-dithiodipropionamide with hydrogen chloride to obtain 2-methyl-4-isothiazolin-3-one hydrochloride salt, then washed with Et acetate, dissolving in water and neutralized with sodium carbonate to generate the product. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Computed Properties of 26172-54-3

The Article related to alkyl isothiazolinone preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Computed Properties of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On December 7, 1983, Bayer, Horst Otto; Lange, Barry Clifford; Petigara, Ramesh Balubhai published a patent.Application In Synthesis of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Biocidal or biostatic compositions containing 3-isothiazolones and their uses. And the patent contained the following:

Compositions of isothiazolones I (R = R1 = H, halo, C1-4 alkyl; R2 = C1-8 alkyl, C3-6 cycloalkyl) were prepared which containing less than 15 ppm of nitrosamine and nitrosamine precursors as impurities. Thus, MeO2CCH2CH2SSCH2CH2CO2Me was amidated with MeNH2 to give 100% MeNHCOCH2CH2SSCH2CH2CONHMe (II) containing 5000 ppm MeNHCH2CH2CONH2 (III). II was recrystallized from PrOH to give II containing 0 ppm. III. II was cyclized by chlorination and Mg(NO3)2 added to the products to give a composition containing 10.3% by weight 5-chloro-2-methyl-4-isothiazolin-3-one, 5.0% by weight 2-methyl-4-isothiazolin-3-one, and 0 ppm nitrosamine and no nitrosamine precursor. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Application In Synthesis of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to isothiazolinone nitrosamine free, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Application In Synthesis of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On April 20, 2018, Chen, Zijin published a patent.Name: 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Antifog-haze low-carbon health coating. And the patent contained the following:

The title coating is prepared from: pure water, pH-adjusting agent, cellulose thickener, dispersion wetting agent, defoamer, super nano-antiradiation anti-fog haze material, nano titanium dioxide, nano far-IR auxiliary agent, heavy calcium carbonate, 828 titanium dioxide, calcined kaolin, antistatic dust remover, VOC-free emulsion or resin, fungicide, nano silver antimicrobial agent and thickening agent. The coating is prepared according to a reasonable formula, and various materials with special functions, such as graphene, nano anion, nano tourmaline, nano titanium dioxide, nano far-IR auxiliary, antistatic dust remover are compounded, so that the resulting coating has good antimildew effect, good dust-proof performance and good antifouling effect and is colorful. The coating is VOC-free, and exhibits good antifog-haze effect, long-lasting air purification, and good antibacterial disinfection effect. The coating can release far IR and neg. oxygen ions. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Name: 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to fluoropolymer eva polystyrene hydroxyethylcellulose sodium polyacrylate coating, Coatings, Inks, and Related Products: Other Coating Materials and other aspects.Name: 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On February 19, 2019, Xie, Zhenwei published a patent.Computed Properties of 26172-54-3 The title of the patent was UV LED water-based ultraviolet curing household furniture coating and preparation method thereof. And the patent contained the following:

Title UV-LED aqueous UV curing household furniture coating comprises: aliphatic urethane acrylate 25~40 parts, aliphatic polyurethane dispersion 45~60 parts, dispersant 0.1 to 0.5 parts, humectant 0.1~0.5 parts, fumed silica 0.1 to 0.5 parts, TS 100 matting powder 1~5 parts, PE wax powder 0.3~0.8 parts, defoamer 0.1~0.5 parts, leveling agent 0.1~0.5 parts, thickener 0.5~3 parts, photoinitiator 2~6 parts, fungicide 0.05~0.3 parts, preservative 0.05~0.3 parts and deionized water 4.8~12.5 parts. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Computed Properties of 26172-54-3

The Article related to polyurethane acrylic uv curable furniture coating preparation, Coatings, Inks, and Related Products: Other Coating Materials and other aspects.Computed Properties of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On July 20, 2016, there was a patent about antibacterial agents.Computed Properties of 26172-54-3 The title of the patent was Waterborne flame-retardant coating containing polyurethane and manufacture method. And the patent contained the following:

Title coating is manufactured from waterborne polyurethane resin 30-80, dispersion wetting agent 10-20, defoaming agent 1-5, antibacterial agent 1-5, film-forming additive 10-20, fireproofing agent 1-10, and water 50-150 weight part. Title coating has good fire resistance and broad prospect for industrial application. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Computed Properties of 26172-54-3

The Article related to waterborne flame retardant coating polyurethane manufacture, Coatings, Inks, and Related Products: Other Coating Materials and other aspects.Computed Properties of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On August 17, 2016, there was a patent about fire-resistant coating materials.Quality Control of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Water-borne flame-retarding coatings. And the patent contained the following:

The water-borne flame-retarding coating is produced by the steps, mixing water-borne polyurethane resin 50 kg, lactic acid 15 kg, Me silicone oil 3 kg, 2-methyl-4-isothiazoline-3-one hydrochloride 2 kg, diethylene glycol Bu ether 15 kg, flame retardant 8 kg, and water 100 kg, and stirring at 1,500 rpm for around 60 min. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Quality Control of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to water borne flame retarding coating, Coatings, Inks, and Related Products: Other Coating Materials and other aspects.Quality Control of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On January 4, 2019, Wang, Songying; Qiu, Zhenming; Huang, Liang; Jiang, Dan published a patent.Formula: C4H6ClNOS The title of the patent was Application of polymer as protease stabilizer in detergents and detergent composition. And the patent contained the following:

Title polymer is an ethoxylated polyethyleneimine. Thus, deionized water was added to the configuration tank; next, 10 weight% of ethoxylated fatty alc. sulfate, 4 weight% of alpha-olefin sulfonate, 7 weight% of ethoxylated fatty alc. 9 and 0.6 weight% of potassium hydroxide were admixed therein, then, protease, 0.05 weight% of 1,2-benzisothiazolin-3-one, 0.05 weight% of 2-methylisothiazolin-3-one and 5-chloro-2-methylisothiazolin-3-one and 1 weight% of polyacrylic acid were mixed thereto, heated, and stirred to obtain the title detergent composition The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Formula: C4H6ClNOS

The Article related to polymer protease stabilizer detergent composition, Surface Active Agents and Detergents: Cleaning Compositions and other aspects.Formula: C4H6ClNOS

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com