Category: 93-02-7

Product Details of 93-02-7. In 2020.0 SYNTHESIS-STUTTGART published article about DIELS-ALDER REACTION; NATURAL-PRODUCTS; EFFICIENT SYNTHESIS; SMALL MOLECULES; DRUGS; ALDEHYDES; CYCLOADDITIONS; INHIBITORS; CHEMISTRY; STRATEGY in [Rehan, Mohammad; Flegel, Jana; Heitkamp, Franziska; Pergomet, Jorgelina L.; Kumar, Kamal] Max Planck Inst Mol Physiol, Abt Chem Biol, Otto Hahn Str 11, D-44227 Dortmund, Germany; [Flegel, Jana; Heitkamp, Franziska; Otte, Felix; Strohmann, Carsten] Tech Univ Dortmund, Fak Chem & Chem Biol, Otto Hahn Str 6, D-44227 Dortmund, Germany in 2020.0, Cited 65.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

An enantioselective hetero-Diels-Alder reaction of alkylidene- oxindoles and 2-aza-3-silyloxy-1,3-butadienes, catalyzed by divalent transition metal complexes withN,N ‘-dioxide ligands offered an efficient access to natural-product-based 3,3 ‘-piperidinoyl spiroox-indole class of small molecules.exo-Cycloadducts formed via stereospecific cycloaddition withZ-olefin displayed potent activity in modulation of hedgehog pathway.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Rehan, M; Flegel, J; Heitkamp, F; Pergomet, JL; Otte, F; Strohmann, C; Kumar, K or concate me.. Product Details of 93-02-7

Reference:
Isothiazole – Wikipedia,
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Application In Synthesis of 2,5-Dimethoxybenzaldehyde. In 2019.0 CELLULOSE published article about LIGNOCELLULOSE FRACTIONATION; ENZYMATIC-HYDROLYSIS; PYROLYSIS; BIOMASS; CHEMICALS; DEPOLYMERIZATION; PRETREATMENT; VALORIZATION; BETA-O-4; PLATFORM in [Lyu, Gaojin; Wu, Qin; Li, Tengfei; Jiang, Weikun; Ji, Xingxiang; Yang, Guihua] Qilu Univ Technol, Shandong Acad Sci, State Key Lab Biobased Mat & Green Papermaking, Jinan 250353, Shandong, Peoples R China in 2019.0, Cited 42.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

In the present examination, the thermochemical behavior of the lignin extracted from willow (Salix matsudana cv. Zhuliu) by deep eutectic solvents (DES) treatment (DES-lignin) with varied times were investigated with the techniques of thermogravimetric analyzer, in situ diffuse reflectance infrared pyrolysis (in situ-FTIR), and pyrolysis-gas chromatography/mass spectrometry. The results showed that thermal degradation of DES-lignin mainly occurred at 185-470 degrees C with two maximum weight loss peaks at 265 degrees C and 380 degrees C respectively, and the solid residue was 40% when terminated at 800 degrees C. The identified cluster of aromatics from in situ-FTIR was detected earlier and stronger than those of small molecular gases, suggesting cleavage of lignin intermolecular linkages dominated the initial pyrolysis process. The DES-lignin was sensitive to pyrolysis to produce aromatics. The total phenols yield from DES-lignin pyrolysis reached a maxima of 95.1% at 450 degrees C, among which phenol and guaiacol accounted for the largest proportion, i.e. 20.8% and 24.2% respectively. In addition, product distribution was remarkably affected by pyrolysis temperature and the DES treatment time used for lignin isolation.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Lyu, GJ; Wu, Q; Li, TF; Jiang, WK; Ji, XX; Yang, GH or concate me.. Application In Synthesis of 2,5-Dimethoxybenzaldehyde

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Recently I am researching about HETEROGENEOUS CATALYST; HIGHLY EFFICIENT; CARBON NANOTUBES; QUINAZOLINONES; FACILE; NITRO, Saw an article supported by the Research Council of Payame Noor University. Published in MAIK NAUKA/INTERPERIODICA/SPRINGER in NEW YORK ,Authors: Fallah-Mehrjardi, M; Kalantari, S. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde. Name: 2,5-Dimethoxybenzaldehyde

In the present study, an efficient and magnetically recoverable Bronsted acid ionic liquid, 1-methyl-3-[3-(triethoxysilyl)propyl]-1H-imidazol-3-ium hydrogen sulfate, immobilized on the surface of Fe3O4@SiO2 magnetic nanoparticles (Fe3O4@SiO2-ImHSO(4)) has been used for a high-yield synthesis of 2,3-dihydroquinazolin-4(1H)-ones through the condensation of anthranilamide with aldehydes and ketones in EtOH at room temperature or under reflux. The significant features of the present protocol are short reaction times, high yields of products, ecofriendly reaction conditions, simple work-up, and reusability of the catalyst. The catalyst can be simply magnetically recovered and reused at least five times without considerable loss of its catalytic activity.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Fallah-Mehrjardi, M; Kalantari, S or concate me.. Name: 2,5-Dimethoxybenzaldehyde

Reference:
Isothiazole – Wikipedia,
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SDS of cas: 93-02-7. In 2019.0 BIOORG CHEM published article about RAPID COLORIMETRIC ASSAY; BIOLOGICAL EVALUATION; DISCOVERY; IDENTIFICATION; MECHANISM; SURVIVAL; TARGETS; FAMILY; GROWTH in [Metwally, Nadia Hanafy; Mohamed, Mona Said; Ragb, Eman Ali] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt in 2019.0, Cited 40.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

A novel series of pyrazolo[1,5-a]pyrimidines were synthesized and proved by their spectral and elemental analysis, some elected of the newly synthesized compounds were examined for their cytotoxic activity employing MTT assay on two cancer cell lines (Breast and Hela cancers). Compounds 5, 7e and 7i showed the higher cytotoxicity against two cancer cell lines with (IC50 = 13.91 +/- 1.4 and 22.37 +/- 1.8 mu M/L), (IC50 = 6.56 +/- 0.5 and 8.72 +/- 0.9 mu M/L) and (IC50 = 4.17 +/- 0.2 and 5.57 +/- 0.4 mu M/L) for two cancer cell lines breast and hela respectively, using doxorubicin as a reference drug. The most potent cytotoxic active compounds 5, 7e and 7i presented inhibitory activity against KDM (histone lysine demethylases) with IC50 = 4.05, 1.91 and 2.31 mu M, respectively. The most potent KDM inhibitor 7e (IC50 = 1.91 mu M) showed to cause cell cycle arrest at G2/M phase by 4 folds than control and induce total apoptotic effect by 10 folds more than control. In silico studies performed on the more potent cytotoxic active compounds 5, 7e and 7i included lipinisk’s rule of five. Moreover, molecular docking study was utilized to explore the binding mode of the most active compounds to the target enzyme (PDB-ID: 5IVE). Also, some bioinformatics studies were carried out for compounds 7e and 7i using Swiss ADME (Swiss Institute of bioinformatics 2018).

SDS of cas: 93-02-7. About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Metwally, NH; Mohamed, MS; Ragb, EA or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Quinoxaline-PABA bipartite hybrid derivatization approach: Design and search for antimicrobial agents WOS:000461047100065 published article about ENTEROTOXIGENIC ESCHERICHIA-COLI; DERIVATIVES; ANTICANCER in [Patel, Harun M.; Sharma, Poonam; Lohan, Sandeep; Bansal, Sumit] RC Patel Inst Pharmaceut Educ & Res, Dept Pharmaceut Chem, Dhule 425405, Maharashtra, India; [Bhardwaj, Varun] Jaypee Univ Informat Technol, Dept Biotechnol Bioinformat & Pharm, Solan 173234, Himachal Prades, India; [Noolvi, Malleshappa N.] Shree Dhanvantary Pharm Coll, Dept Pharmaceut Chem, Surat 394110, Gujarat, India; [Sharma, Amit] Postgrad Inst Med Educ & Res PGIMER, Sch Publ Hlth, Chandigarh 160012, India in 2019.0, Cited 30.0. Application In Synthesis of 2,5-Dimethoxybenzaldehyde. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7

In an attempt to find a new class of antimicrobial agents, in the present study we report the synthesis of bipartite hybrid styryl derivatives of quinoxaline containing para-aminobenzoic acid (PABA) and their biological evaluation as antimicrobial agents. The series of new substituted styryl based derivatives 5(a-k) were evaluated for antimicrobial potential against various bacteria including Staphylococcus aureus, Vibrio cholerae, Escherichia coli, Bacillus subtilis, Escherichia coli, Mycobacterium smegmatis, Pseudomonas aeruginosa and fungi; C. albicans, with ampicillin and amphotericin B as standards. Similarly these compounds were also screened for anti-cancer activity using MCF-7 cell line. Among the synthesized compounds, 5(c) was observed to be the most active compound against various strains with MIC in a range of 7.9-31 mu M of the series and compound 5i came out with significant anti-cancer activity with IC50 value of 7 mu M. (C) 2019 Elsevier B.V. All rights reserved.

Application In Synthesis of 2,5-Dimethoxybenzaldehyde. About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Patel, HM; Bhardwaj, V; Sharma, P; Noolvi, MN; Lohan, S; Bansal, S; Sharma, A or concate me.

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

Application In Synthesis of 2,5-Dimethoxybenzaldehyde. In 2020 J CHEM SCI published article about ANTIPROLIFERATIVE ACTIVITY in [Huynh, Thi-Kim-Chi; Nguyen, Thanh-Danh; Hoang, Thi-Kim-Dung] VAST, Inst Chem Technol, 01 Mac Dinh Chi Str,Dist 1, Ho Chi Minh City, Vietnam; [Huynh, Thi-Kim-Chi; Hoang, Thi-Kim-Dung] VAST, Grad Univ Sci & Technol, 18 Hoang Quoc Viet Str, Hanoi, Vietnam; [Nguyen, Thi-Hong-An] Ton Duc Thang Univ, 19 Nguyen Huu Tho Str,Dist 7, Ho Chi Minh City, Vietnam; [Tran, Ngoc-Hoang-Son] Ho Chi Minh City Univ Technol, 268 Ly Thuong Kiet Str,Dist 10, Ho Chi Minh City, Vietnam in 2020, Cited 20. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

This study reports a simple process to synthesize and separate of 2-(substituted-phenyl) benzimidazole derivatives with high yield and efficiency. Specifically, by reacting ortho-phenylenediamines with benzaldehydes using sodium metabisulphite as an oxidation agent in a mixture of solvent under mild condition, twenty-three compounds of benzimidazoles were obtained and separated easily using hexane and water to wash, respectively. The structure of all obtained compounds was identified by FTIR, NMR and HRMS. The SAR analysis of synthesized benzimidazoles on human lung (A549), breast (MDA-MB-231) and prostate (PC3) cancer cell lines showed that the presence of methyl group at 5(6)-position on benzimidazole scaffold was a contributing factor influencing the anticancer activity. The presence of electron-donating groups (OH, OMe, -NMe2, -O-CH2-C6H5) also caused significant increase of anticancer activity, while the presence of electron-withdrawing groups (-NO2, -CF3) on the phenyl group at 2-position of benzimidazole ring decreased the ability of inhibition of synthesized benzimidazoles. The compounds 2f and 2g displayed the significant anticancer activity on both A549 and PC3 cell lines.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Huynh, TKC; Nguyen, THA; Tran, NHS; Nguyen, TD; Hoang, TKD or concate me.. Application In Synthesis of 2,5-Dimethoxybenzaldehyde

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Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

An article Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action WOS:000489305700020 published article about BETA-HEMATIN FORMATION; IN-VITRO; POTENTIAL ANTIMALARIAL; MOLECULAR-MECHANISM; HEMOZOIN FORMATION; MALARIA; ANTICANCER; QUERCETIN; DERIVATIVES; INHIBITION in [Charris, Jaime E.; Monasterios, Melina C.; Acosta, Maria E.; Rodriguez, Miguel A.; Gamboa, Neira D.] Cent Univ Venezuela, Fac Pharm, Biochem Unit, Organ Synth Lab, Los Chaguaramos 1041-A, Caracas 47206, Venezuela; [Martinez, Gricelis P.; Mijares, Michael R.] Cent Univ Venezuela, Fac Pharm, Biotechnol Unit, Los Chaguaramos 1041-A, Caracas 47206, Venezuela; [Rojas, Hector R.; Mijares, Michael R.; De Sanctis, Juan B.] Cent Univ Venezuela, Fac Med, Inst Immunol, Los Chaguaramos 1050-A, Caracas 50109, Venezuela; [De Sanctis, Juan B.] Palacky Univ, Fac Med, Inst Mol & Translat Med, Hnevotinska 1333-5, Olomouc 77900, Czech Republic in 2019, Cited 62. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7. Quality Control of 2,5-Dimethoxybenzaldehyde

A series of quinoline-chalcone (E)-1-[3 or 4-(7-chloroquinolin-4-ylamino) phenyl]-3-(phenyl substituted) prop-2-ene-1-one (4, 5), and quinoline-pyrazoline hybrids 7-Chloro-N-[3 or 4-(4,5-dihydro-5-(phenyl-substituted)-1H-pyrazol-3-yl] phenyl) quinoline-4-amine (6, 7) were synthesized with the aim of achieving an antimalarial and anticancer dual action. Most of the compounds showed significant inhibition (%>80) of beta-hematin formation. The existing structures were tested in vivo as potential antimalarials in mice infected with P. berghei ANKA, chloroquine susceptible strain. Some of the compounds exhibited antimalarial activity comparable to that of chloroquine. Moreover, the compounds induce cell death on two human cancer cell lines (Jurkat E6.1 and HL60) without affecting the primary culture of human lymphocytes. Flow cytometry analysis confirmed the increase in apoptotic cell death after 24 h. Based on the structural analysis, these quinoline hybrids represent new compounds potentially useful for malaria end leukemia treatments.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Charris, JE; Monasterios, MC; Acosta, ME; Rodriguez, MA; Gamboa, ND; Martinez, GP; Rojas, HR; Mijares, MR; De Sanctis, JB or concate me.. Quality Control of 2,5-Dimethoxybenzaldehyde

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Isothiazole – Wikipedia,
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Formula: C9H10O3. Shalini; Pankaj; Saha, ST; Kaur, M; Oluwakemi, E; Awolade, P; Singh, P; Kumar, V in [Shalini; Pankaj; Kumar, Vipan] Guru Nanak Dev Univ, Dept Chem, Amritsar 143005, Punjab, India; [Saha, Sourav Taru; Kaur, Mandeep] Univ Witwatersrand, Sch Mol & Cell Biol, Private Bag 3, ZA-2050 Johannesburg, South Africa; [Oluwakemi, Ebenezer; Awolade, Paul; Singh, Parvesh] Univ Kwazulu Natal, Sch Chem & Phys, P Bag X54001, ZA-4000 Durban, South Africa published Synthesis and in vitro anti-proliferative evaluation of naphthalimide-chalcone/pyrazoline conjugates as potential SERMs with computational validation in 2020.0, Cited 39.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.

A series of naphthalimide-chalcone/pyrazoline conjugates was prepared and evaluated for their anti-breast cancer potential against estrogen responsive, i.e. MCF-7 (ER+), and triple-negative, i.e. MDA-MB-231 (ER-), cell lines. The structure-activity-relationship (SAR) was deduced based on the influence of linker length, substituents on the phenyl ring and the generated functionalities, on anti-proliferative activities. Docking simulations further delineate the type of interactions of the designed molecules with the selected targets. This report discloses the scope of triazole tethered naphthalimide-chalcone/pyrazoline conjugates as anti breast cancer agents.

Formula: C9H10O3. About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Shalini; Pankaj; Saha, ST; Kaur, M; Oluwakemi, E; Awolade, P; Singh, P; Kumar, V or concate me.

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Quality Control of 2,5-Dimethoxybenzaldehyde. Authors Przhevalskii, NM; Laypanov, RK; Tokmakov, GP; Lukina, IV; Vershinkin, DA; Tafeenko, VA in SPRINGER published article about in [Przhevalskii, N. M.; Laypanov, R. K.; Tokmakov, G. P.; Lukina, I., V; Vershinkin, D. A.] Russian State Agr Univ, Moscow Timiryazev Agr Acad, 49 Ul Timiryazevskaya, Moscow 127434, Russia; [Tafeenko, V. A.] Lomonosov Moscow State Univ, Dept Chem, Build 3,1 Leninskie Gory, Moscow 119992, Russia in 2021.0, Cited 24.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7

New pyranopyridonotryptamines 3 were synthesized by a three-component reaction of pyridonotryptamines 1, aromatic aldehydes 2, and malononitrile. The structures of compounds 3 were confirmed by X-ray crystallography. A series of compounds 3 underwent primary screening for the effect on the course of mitosis in seeds of plants of the species Allium cepa L.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Przhevalskii, NM; Laypanov, RK; Tokmakov, GP; Lukina, IV; Vershinkin, DA; Tafeenko, VA or concate me.. Quality Control of 2,5-Dimethoxybenzaldehyde

Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com

In 2020 CHEMISTRYSELECT published article about GREEN FLUORESCENT PROTEIN; GFP CHROMOPHORE ANALOGS; ENHANCEMENT; CHEMISTRY; MIMICS; YLIDES; PROBE in [Sokolov, Anatolii I.; Myasnyanko, Ivan N.; Baleeva, Nadezhda S.; Baranov, Mikhail S.] Russian Acad Sci, Inst Bioorgan Chem, Miklukho Maklaya 16-10, Moscow 117997, Russia; [Baranov, Mikhail S.] Russian Acad Sci, Pirogov Russian Natl Russia Res Med Univ Inst Bio, Miklukho Maklaya 16-10, Moscow 117997, Russia in 2020, Cited 34. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7. Recommanded Product: 2,5-Dimethoxybenzaldehyde

We propose a new protocol for synthesis of the arylidene-1H-imidazol-5(4H)-ones which is based onO-alkylation of amidoacetates using triethyloxonium tetrafluoroborate leading to carboximidates. These imidates have long been used in the synthesis of imidazolones by [2+3] cycloaddition reaction with Schiff bases. However, diversity of carboximidates prepared by the common techniques was limited. The protocol we proposed eliminated these limitations. Using this technique, a number of derivatives of the green fluorescent protein (GFP) and asFP chromophores were synthesized, and influence of the C2 residue on their optical properties was studied.

About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Sokolov, AI; Myasnyanko, IN; Baleeva, NS; Baranov, MS or concate me.. Recommanded Product: 2,5-Dimethoxybenzaldehyde

Reference:
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