Category: 35272-19-6

《1,2,3-Benzothiadiazoles. V. Rearrangement of diazonium salts derived from 7-aminobenzisothiazoles》 was published in Journal of the Chemical Society [Section] C: Organic in 1971. These research results belong to Haddock, E.; Kirby, P.; Johnson, A. W.. SDS of cas: 35272-19-6 The article mentions the following:

Sandmeyer decomposition of 6 diazotized 7-aminobenzisothiazoles gave 1,2,3-benzothiadiazole-7-carboxaldehydes (I), but hypophosphorous acid decomposition removed the diazonium group. Decomposition of 4-chlorobenzisothiazole-7-diazonium chloride with CrCl2, SnCl2, Cu2Cl2, and FeCl2 in HCl showed that the relative extent of these competing reactions is governed by the oxidation potential for the metal cation to its higher oxidation state. In the experiment, the researchers used many compounds, for example, 3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6SDS of cas: 35272-19-6)

3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. It has been found that isothiazole-based compounds show synergistic effects when used with other biocidal compounds.SDS of cas: 35272-19-6 These molecules also act as herbicides and in combination with other herbicidal molecules they often enhance their efficacy.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Clarke, Kenneth; Gleadhill, Brian; Scrowston, Richard M. published an article in Journal of Chemical Research, Synopses. The title of the article was 《Condensed isothiazoles. Part 7. Substitution reactions of 3-methyl-1,2-benzisothiazole and some of its 4- and 5-substituted derivatives》.Reference of 3-Methyl-5-nitrobenzoisothiazole The author mentioned the following in the article:

Some electrophilic formylation, chlorination, bromination and nitration reactions of the methylbenzisothiazole derivatives I (R = R1 = H; R = Br, NH2, NHAc, OH, OMe, R1 = H; R = H, R1 = Br) are described. I (R = H, R1 = Cl, Br, NO2) were prepared by deamination of the appropriate substitution products I (R = NH2, R1 = Cl, Br, NO2). Improved syntheses of 7-chloro- and -bromo-3-methyl-1,2-benzisothiazole are also reported. In addition to this study using 3-Methyl-5-nitrobenzoisothiazole, there are many other studies that have used 3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6Reference of 3-Methyl-5-nitrobenzoisothiazole) was used in this study.

3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. Various penicillins and cephalosporins having an isothiazole ring system have shown considerable antibacterial efficacy against Gram-positive and Gram-negative bacteria. Reference of 3-Methyl-5-nitrobenzoisothiazoleMany compounds with an isothiazole scaffold demonstrated a wide range of biological profiles, including antiinflammatory, antithrombotic, and anticonvulsive agents.Some of these molecules have been efficiently used in the treatment of Alzheimer’s disease.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Name: 3-Methyl-5-nitrobenzoisothiazoleOn May 31, 1991, McKinnon, David M.; Abouzeid, A. A. published an article in Journal of Heterocyclic Chemistry. The article was 《Substituent interaction with ring sulfur in some heterocyclic compounds》. The article mentions the following:

The IR carbonyl absorptions of acetylbenzisothiazoles I (R, R1, R2 = H, COMe, SMe) are similar to 7-acetylbenzo[b]thiophenes, but are lower by approx. 15 cm-1 than the corresponding benzo[b]furans. The reasons for this are discussed. The results came from multiple reactions, including the reaction of 3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6Name: 3-Methyl-5-nitrobenzoisothiazole)

3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. Various penicillins and cephalosporins having an isothiazole ring system have shown considerable antibacterial efficacy against Gram-positive and Gram-negative bacteria. Name: 3-Methyl-5-nitrobenzoisothiazoleMany compounds with an isothiazole scaffold demonstrated a wide range of biological profiles, including antiinflammatory, antithrombotic, and anticonvulsive agents.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

《One-Pot Synthesis of Substituted 2-Aminobenzo[b]thiophenes》 was written by Solovyev, Andrey Y.; Androsov, Dmitry A.; Neckers, Douglas C.. Application In Synthesis of 3-Methyl-5-nitrobenzoisothiazole And the article was included in Journal of Organic Chemistry on April 13 ,2007. The article conveys some information:

Reaction of 1-(2-chloro-5-nitrophenyl)ethanone via Willgerodt-Kindler routes using primary and secondary amines resulted in a simple, efficient, three-component one-pot synthesis of 2-aminobenzo[b]thiophenes, e.g., I (R = Me, allyl, Bu, CH2Ph, CHMe2, cyclopentyl, cyclohexyl).3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6Application In Synthesis of 3-Methyl-5-nitrobenzoisothiazole) was used in this study.

3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. It has been found that isothiazole-based compounds show synergistic effects when used with other biocidal compounds. These molecules also act as herbicides and in combination with other herbicidal molecules they often enhance their efficacy.Application In Synthesis of 3-Methyl-5-nitrobenzoisothiazole

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

The author of 《Microwave-assisted synthesis of benzisothiazoles and benzisoselenazoles》 were Rais, Afsha; Ankati, Haribabu; Biehl, Ed. And the article was published in Trends in Heterocyclic Chemistry in 2009. Related Products of 35272-19-6 The author mentioned the following in the article:

A microwave-mediated preparation and possible mechanism of benzisothiazole and benzisoselenazole formation are presented. The synthesis of the target compounds [i.e., 3-methyl-1,2-benzisothiazol-5-amine, 3-methyl-1,2-benzisoselenazol-5-amine] was achieved using sulfur or selenium and 1-(2-chloro-5-nitrophenyl)ethanone and ammonium acetate as starting materials. The experimental process involved the reaction of 3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6Related Products of 35272-19-6)

3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. Various penicillins and cephalosporins having an isothiazole ring system have shown considerable antibacterial efficacy against Gram-positive and Gram-negative bacteria. Related Products of 35272-19-6Many compounds with an isothiazole scaffold demonstrated a wide range of biological profiles, including antiinflammatory, antithrombotic, and anticonvulsive agents.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Synthetic Route of C8H6N2O2SOn March 27, 2010, Androsov, Dmitry A.; Solovyev, Andrey Y.; Petrov, Mikhail L.; Butcher, Ray J.; Jasinski, Jerry P. published an article in Tetrahedron. The article was 《A convenient approach towards 2- and 3-aminobenzo[b]thiophenes》. The article mentions the following:

Reaction of 1-(2-chloro-5-nitrophenyl)ethanone via Willgerodt-Kindler route with primary or secondary amines and sulfur allows a simple, efficient one-pot synthesis of 3-aminobenzo[b]thiophenes. Base-catalyzed transformation of 4-(2-chloro-5-nitrophenyl)-1,2,3-thiadiazole in the presence of primary and secondary amines offers a convenient approach towards 2-aminobenzo[b]thiophenes. In the experiment, the researchers used 3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6Synthetic Route of C8H6N2O2S)

3-Methyl-5-nitrobenzoisothiazole(cas: 35272-19-6) belongs to isothiazole. Various penicillins and cephalosporins having an isothiazole ring system have shown considerable antibacterial efficacy against Gram-positive and Gram-negative bacteria. Synthetic Route of C8H6N2O2SSome of these molecules have been efficiently used in the treatment of Alzheimer’s disease.

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com