Category: 26172-54-3

On April 20, 2018, Chen, Zijin published a patent.Name: 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Antifog-haze low-carbon health coating. And the patent contained the following:

The title coating is prepared from: pure water, pH-adjusting agent, cellulose thickener, dispersion wetting agent, defoamer, super nano-antiradiation anti-fog haze material, nano titanium dioxide, nano far-IR auxiliary agent, heavy calcium carbonate, 828 titanium dioxide, calcined kaolin, antistatic dust remover, VOC-free emulsion or resin, fungicide, nano silver antimicrobial agent and thickening agent. The coating is prepared according to a reasonable formula, and various materials with special functions, such as graphene, nano anion, nano tourmaline, nano titanium dioxide, nano far-IR auxiliary, antistatic dust remover are compounded, so that the resulting coating has good antimildew effect, good dust-proof performance and good antifouling effect and is colorful. The coating is VOC-free, and exhibits good antifog-haze effect, long-lasting air purification, and good antibacterial disinfection effect. The coating can release far IR and neg. oxygen ions. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Name: 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to fluoropolymer eva polystyrene hydroxyethylcellulose sodium polyacrylate coating, Coatings, Inks, and Related Products: Other Coating Materials and other aspects.Name: 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On May 24, 2017, Li, Xiaobin; Wang, Jianguo; Wang, Xinhai; Liu, Liming published a patent.Computed Properties of 26172-54-3 The title of the patent was Preparation method of high-purity 2-alkyl-4-isothiazolin-3-one. And the patent contained the following:

A process for preparation of high-purity 2-alkyl-4-isothiazolin-3-one is disclosed. The process comprises reaction of N,N’-dimethyl-3,3′-dithiodipropionamide with hydrogen chloride to obtain 2-methyl-4-isothiazolin-3-one hydrochloride salt, then washed with Et acetate, dissolving in water and neutralized with sodium carbonate to generate the product. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Computed Properties of 26172-54-3

The Article related to alkyl isothiazolinone preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Computed Properties of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On October 2, 2001, Onishi, Toshikiyo; Toujou, Tamaki; Noguchi, Keiji published a patent.Application In Synthesis of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Preparation of metal-free stable liquid compositions containing 3-isothiazolones as industrial bactericides. And the patent contained the following:

The compositions are prepared by dissolving hydrogen halide salts of 3-isothiazolones in PhOH and washing the solution with water to remove the acids. Thus, a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one hydrochloride (I.HCl) and 2-methyl-4-isothiazolin-3-one hydrochloride was dissolved in PhOH, mixed with water, the aqueous phase removed, and the PhOH phase was washed with water to give a solution containing 21.8% I. The solution was left at 40° for 4 wk in a sealed container to show I content 19.6%. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Application In Synthesis of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to decomposition chloromethylisothiazolinone hydrochloride bactericide phenol water, industrial antibacterial agents and other aspects.Application In Synthesis of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On August 29, 1974, Weiler, Ernest D. published a patent.Reference of 2-Methylisothiazol-3(2H)-one hydrochloride The title of the patent was Bactericidal and fungicidal 4,5,5-trichloro-3-isothiazolidinones. And the patent contained the following:

Seventeen isothiazolidinones (I; R = C1-10 alkyl, CH2Ph, Ph, C6H4Cl-3, CHMePh, or cyclohexyl; R1 = Me or Cl) were prepared and used as bactericides and fungicides. Thus, (MeNHCOCHMeCH2S)2 was treated with Cl to give 19% I (R = R1 = Me), which was also prepared in 68% yield by chlorination of 2,4-dimethyl-4-isothiazolin-3-one in AcOEt at ≤67°. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Reference of 2-Methylisothiazol-3(2H)-one hydrochloride

The Article related to chloroisothiazolidinone bactericide fungicide, isothiazolidinone bactericide, fungicides and other aspects.Reference of 2-Methylisothiazol-3(2H)-one hydrochloride

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On November 26, 1992, Hahn, Soon Jong; Kim, Jin Man; Park, Young published a patent.Synthetic Route of 26172-54-3 The title of the patent was Preparation of N-alkyl-4-isothiazolin-3-ones from dithiodipropionamides and sulfuryl halides. And the patent contained the following:

Title compounds [I; R1 = Me, Me(CH2)7; R2 = H, Cl], were prepared by (1) treatment of (SCH2CH2CO2H)2 with SOCl2 to give (SCH2CH2COCl)2, (2) treatment of the latter with R1NH2 to give (SCH2CH2CONHR1)2, and (3) treatment of this with SO2X2 (X = halo) in an organic solvent. Thus, [SCH2CH2CONH(CH2)7Me]2 was treated with SO2Cl2 in CH2Cl2 at 0-25° to give 90.5% title compound II. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Synthetic Route of 26172-54-3

The Article related to dithiodipropionamide sulfuryl halide cyclocondensation alkylisothiazolinone, cyclocondensation reaction and other aspects.Synthetic Route of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On October 25, 1995, Petigara, Ramesh Balubbai published a patent.Synthetic Route of 26172-54-3 The title of the patent was Purification of 3-isothiazolones. And the patent contained the following:

The title process for producing substantially separated 5-chloro-2-methyl-3-isothiazolone (CMI) and 2-methyl-3-isothiazolone (MI) from a mixture of their hydrochloride salts comprises heating a mixture of CMI.HCI and MI.HCI in an org, solvent for a period of time necessary to fully dissociate CMI.HCI but insufficient to fully dissociate MI.HCI. CMI free base dissolves in the solvent and the products may recovered by filtration. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Synthetic Route of 26172-54-3

The Article related to chloromethylisothiazolone purification, methylisothiazolone purification, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Synthetic Route of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On June 17, 1992, Petigara, Ramesh Balubhai; Horton, Isaac Byron published a patent.Computed Properties of 26172-54-3 The title of the patent was Process for preparing 3-isothiazolone compounds. And the patent contained the following:

A process for the preparation of salt-free, and optionally water-free, isothiazolones comprising treating a solution of an acid salt of an isothiazolone with a basic anion exchange resin, preferably a weak base anion exchange resin, and separating the free base isothiazolone solution from the spent resin is claimed. Five different ion exchange resins were evaluated: two strong base anion exchange resins (Amberlite IRA-9OOC-OH and IRA-420C-OH) and 3 weak base anion exchange resins (Amberlite IRA-68, Amberlyst A21 and Diaion WA-30) were used. Thus, chlorination of N-methyl-3-mercaptopropionamide in EtOAc gave a mixture of HCl salts of 5-chloro-2-methyl-3-isothiazolinone and 2-methyl-3-isothiazolone which were neutralized with the described resins. The resultant salt-free isothiazolones are useful as microbicides in environments where even low concentrations of metal salts are undesirable, for example, latex emulsions and corrosion sensitive aqueous systems. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Computed Properties of 26172-54-3

The Article related to isothiazolone hydrochloride salt preparation neutralization resin, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Computed Properties of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

Weiler, E. D.; Miller, G. A.; Hausman, M. published an article in 1976, the title of the article was Isothiazoles. VIII: isothiazolidin-3-one derivatives.Category: isothiazole And the article contains the following content:

The isothiazolidinone I (R = R1 = Me) was prepared by cyclization of (MeNHCOCHMeCH2)2S2 in EtOAc in the presence of Cl and I (R, R1 given: Me, Cl; Bu, Me; Bu, Cl; CH2Ph, Cl; CH2C6H3Cl2-3,4, Cl) were obtained by the addition of Cl to the appropriate isothiazolinones II. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Category: isothiazole

The Article related to isothiazolidinone trichloro, thiazolinone addition chlorine, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Category: isothiazole

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On April 6, 2011, Jiang, Zhikai; Jiang, Yifan published a patent.Electric Literature of 26172-54-3 The title of the patent was A process for preparing isothiazolone derivatives. And the patent contained the following:

The invention relates to a process for the preparation of isothiazolone derivatives I or II, wherein R1 is H, alkyl, cycloalkyl, or (un)substituted aryl; R2 and R3 independently = H or Cl. For instance, 1,2-benzisothiazol-3(2H)-one was prepared from 2-mercapto-benzonitrile in the presence of Cl2 in 82.28% yield. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).Electric Literature of 26172-54-3

The Article related to isothiazolone derivative preparation heterocyclization, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Electric Literature of 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com

On January 21, 2009, Li, Shaotong published a patent.SDS of cas: 26172-54-3 The title of the patent was Method for synthesizing alkyl isothiazolone hydrochloride by chlorination-cyclization of alkyl dithiodipropionamide with chlorine and sulfuryl chloride. And the patent contained the following:

The invention relates to a method for synthesizing alkyl isothiazolone hydrochloride by chlorination-cyclization of alkyl dithiodipropionamide or alkyl thiopropionamide with chlorine and sulfuryl chloride. The method has advantages of simple operation, low cost and high conversion rate. The experimental process involved the reaction of 2-Methylisothiazol-3(2H)-one hydrochloride(cas: 26172-54-3).SDS of cas: 26172-54-3

The Article related to thiazolone methyl hydrochloride preparation, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.SDS of cas: 26172-54-3

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com