Mardones, Lucas E. et al. published their research in Progress in Organic Coatings in 2018 | CAS: 1003-07-2

Isothiazol-3(2H)-one (cas: 1003-07-2) belongs to isothiazole derivatives. Isothiazole is a good solvent for many organic substances but should be used with caution because it is more toxic than pyridine. It has been found that isothiazole-based compounds show synergistic effects when used with other biocidal compounds.Product Details of 1003-07-2

Long-lasting isothiazolinone-based biocide obtained by encapsulation in micron-sized mesoporous matrices was written by Mardones, Lucas E.;Legnoverde, Maria S.;Pereyra, Andrea M.;Basaldella, Elena I.. And the article was included in Progress in Organic Coatings in 2018.Product Details of 1003-07-2 This article mentions the following:

The physicochem. properties of the silicas (structure, textural properties) were evaluated by SEM, TEM, XRD and adsorption/desorption of N2 in order to determine their ability to encapsulate, stabilize and subsequently release a com. biocide used for latex preservation (CMIT/MIT). CMIT/MIT consists of an aqueous solution of the active ingredients CMIT (5-chloro-2-methyl-4-isothiazolin-3-one) and MIT (2-methyl-4-isothiazolin-3-one), present in a CMIT/MIT: 3/1 wt ratio. MCF has less hindered diffusion caused by a short channel length, which facilitates the biocide access to the pores of the matrix. The long pore length of SBA-15 makes the diffusion of CMIT/MIT mixture more difficult. Biocide release tests in aqueous media indicated that the CMIT/MIT concentration in the leaching solution depends on the matrix nature, the smaller values being obtained when the ordered matrix was used. Addnl., biocide delivery could be delayed by increasing the working pH from 7 to 9. Results showed that biocide encapsulation allows maintaining a long-lasting release, even under alk. conditions (pH 9), at which the hydrolysis of non-supported CMIT occur. Several release tests at different temperature (318, 323 and 328 K), were carried out for 20 days at pH 7. The biocide loading after the tests was reflected in the IR spectra, and it has been corroborated that biocide encapsulation allows retarding the fast thermal decomposition of CMIT. In the experiment, the researchers used many compounds, for example, Isothiazol-3(2H)-one (cas: 1003-07-2Product Details of 1003-07-2).

Isothiazol-3(2H)-one (cas: 1003-07-2) belongs to isothiazole derivatives. Isothiazole is a good solvent for many organic substances but should be used with caution because it is more toxic than pyridine. It has been found that isothiazole-based compounds show synergistic effects when used with other biocidal compounds.Product Details of 1003-07-2

Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com