Bunnage, Mark E.; Davies, Stephen G.; Goodwin, Christopher J.; Ichihara, Osamu published the artcile< An expeditious asymmetric synthesis of allophenylnorstatine>, Formula: C10H15NO3S, the main research area is asym synthesis allophenylnorstatine; norstatine allophenyl asym synthesis.
The title compound, (2S,3S)-3-amino-2-hydroxy-4-phenylbutanoic acid, a novel amino acid found in the kynostatin class of HIV-1 protease inhibitors, was prepared in 39% overall yield via a tandem conjugate addition-electrophilic hydroxylation protocol using lithium (S)-(α-methylbenzyl)benzylamide and (+)-(camphorsulfonyl)oxaziridine. An unprecedented level of mol. recognition between a homochiral β-amino enolate and a homochiral oxaziridine is identified and the importance of enolate geometry upon hydroxylation stereoselectivity is also addressed.
Tetrahedron published new progress about Stereoselective synthesis. 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Formula: C10H15NO3S.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com