Davis, Franklin A.; Kumar, Anil; Reddy, Rajarathnam E.; Chen, Bang Chi; Wade, Peter A.; Shah, Sharmila W. published the artcile< Hydroxylation of dihydroisoxazoles using N-sulfonyloxaziridines>, Electric Literature of 104322-63-6, the main research area is hydroxylation dihydroisoxazole sulfonyloxaziridine; isoxazole dihydro hydroxylation; stereoselective hydroxylation dihydroisoxazole; oxaziridine sulfonyl hydroxylation.
Enantiomerically enriched 4-isoxazolols I (R = Ph, PhS, PhSO2, PhO, R1 = H; R = Ph, R1 = Bu) (26-71% ee) with predictable absolute configuration are available in good yield by hydroxylation of the aza-enolates of 4,5-dihydroisoxazoles (DHI’s) II with (camphorsulfonyl)oxaziridines III (X = H, Cl, MeO). This method is recommended over other oxidation procedures for the preparation of I because of its efficiency, ability to produce chiral products and the avoidance of toxic HMPA.
Journal of Organic Chemistry published new progress about Hydroxylation, stereoselective. 104322-63-6 belongs to class isothiazole, and the molecular formula is C10H15NO3S, Electric Literature of 104322-63-6.
Referemce:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com