The important role of Benzo[d]isothiazole

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272-16-2, In an article, published in an article,authors is Braibanti, Antonio, once mentioned the application of 272-16-2, Name is Benzo[d]isothiazole,molecular formula is C7H5NS, is a conventional compound. this article was the specific content is as follows.

SPECTROSCOPIC PROPERTIES AND PROTONATION EQUILIBRIA IN 1,2-BENZISOTHIAZOLES

The protonation equilibria of 1,2-benzisothiazoles, involving substituents at position 3, or the ring nitrogen at position 2, have been investigated by potentiometric and/or spectrophotometric methods.The values of the protonation constants (log Kobs) have been compared with values calculated according to the linear relationships of Barlin and Perrin.For compounds with substituents at position 3, the protonation constants have been determined potentiometrically.The presence of the benzisothiazole moiety induces an increase of base strength, with respect to that expected from the calculated substituent effects according to Barlin and Perrin.The protonation constants of the heterocyclic nitrogen at position 2 have been determined spectroscopically in very acidic solutions.The comparison of the values observed with those calculated following Barlin and Perrin for substituted isoquinoline shows that the ring nitrogen is less basic than expected.

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Reference£º
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com