Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 119639-24-6, is researched, SMILESS is O=C(C=C1)N(C(C)(C)C)S1(=O)=O, Molecular C7H11NO3SJournal, Helvetica Chimica Acta called Tilcotil studies. [3+2]Additions with isothiazol-3(2H)-one 1,1-dioxide, Author is Burri, Kaspar F., the main research direction is isothiazolone dioxide regiospecific cycloaddition; tenoxicam analog; piroxicam analog; safety pyrazoloisothiazolone dioxide preparation.Recommanded Product: 2-(tert-Butyl)isothiazol-3(2H)-one 1,1-dioxide.
Derivatives of isothiazol-3(2H)-one 1,1-dioxide (I) react regiospecifically with 1,3-dipolar agents. The main regiocontrolling factor is the C:O group of the dipolarophile. The topol. of the adducts is also in general agreement with predictions based on perturbation theory. Several adducts can be aromatized to heterocyclic equivalents of saccharin, and can then be elaborated into structural analogs of tenoxicam (Tilcotil) and piroxicam (Feldene).
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Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com