Research on new synthetic routes about 6307-44-4

If you want to learn more about this compound(2-Amino-6-methylpyrimidine-4-thiol)Name: 2-Amino-6-methylpyrimidine-4-thiol, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(6307-44-4).

Name: 2-Amino-6-methylpyrimidine-4-thiol. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 2-Amino-6-methylpyrimidine-4-thiol, is researched, Molecular C5H7N3S, CAS is 6307-44-4, about Aryl ethers of 4-[(2-hydroxyethyl)sulfanyl]pyrimidine derivatives: Pathways of synthesis and fungicidal activity of their salt forms. Author is Erkin, A. V.; Klaptyuk, I. V.; Gurzhii, V. V.; Yuzikhin, O. S.; Krutikov, V. I..

2-Amino-4-[(2-aryloxyethyl)sulfanyl]-6-methylpyrimidines were obtained by S-alkylation of 2-amino-6-methylpyrimidin-4(3H)-thione with 2-aryloxyethyl chlorides. Since 2-amino-4-[(2-chloroethyl)sulfanyl]-6-methylpyrimidine is prone to in situ intramol. cyclization it cannot be used in Claisen reaction. The bromination of the target compounds provided 5-bromo derivatives; some of their hydrochlorides exhibited fungicidal activity.

If you want to learn more about this compound(2-Amino-6-methylpyrimidine-4-thiol)Name: 2-Amino-6-methylpyrimidine-4-thiol, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(6307-44-4).

Reference:
Isothiazole – Wikipedia,
Isothiazole – ScienceDirect.com