HPLC of Formula: C9H10O3. Recently I am researching about ANTITUBERCULAR EVALUATION; POTENTIAL ANTICANCER; PYRAZOLINES; IDENTIFICATION; ANTIBACTERIAL; ANTIFUNGAL; AGONISTS; ANALOGS; MOIETY, Saw an article supported by the Dean’s office of College of Pharmacy and Health Sciences, Ajman University, UAE. Published in MDPI in BASEL ,Authors: Shaik, A; Bhandare, RR; Palleapati, K; Nissankararao, S; Kancharlapalli, V; Shaik, S. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde
Our previous work identified isoxazole-based chalcones and their dihydropyrazole derivatives as two important five-membered heterocycles having antitubercular activity. Hence, in the present study, we biologically evaluated 30 compounds, including 15 isoxazole ring-containing chalcones (17-31) and 15 dihydropyrazoles (32-46) derived from these chalcones for their antimicrobial, antioxidant, and anticancer activities. Chalcones exhibited superior antibacterial and antioxidant activities compared to dihydropyrazoles. Among the chalcones, compound 28 showed potent antibacterial (MIC = 1 mu g/mL) and antioxidant activities (IC50 = 5 +/- 1 mu g/mL). Dihydropyrazoles, on the contrary, demonstrated remarkable antifungal and anticancer activities. Compound 46 (IC50 = 2 +/- 1 mu g/mL) showed excellent antifungal activity whereas two other dihydropyrazoles 45 (IC50 = 2 +/- 1 mu g/mL) and 39 (IC50 = 4 +/- 1 mu g/mL) exhibited potential anticancer activity. The compounds were also tested for their toxicity on normal human cell lines (LO2) and were found to be nontoxic. The active compounds that have emerged out of this study are potential lead molecules for the development of novel drugs against infectious diseases, oxidative stress, and cancer.
HPLC of Formula: C9H10O3. Bye, fridends, I hope you can learn more about C9H10O3, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com