An article Regioselective Synthesis of Polyfunctional Arenes by a 4-Component Catellani Reaction WOS:000558679600022 published article about PALLADIUM-CATALYZED ALKYLATION; C-H FUNCTIONALIZATION; ARYL IODIDES; ROUTE; PD/NORBORNENE; HETEROCYCLES; ARYLATION; ACYLATION; ACYLATION/ALKENYLATION; EFFICIENT in [Wang, Jing; Qin, Cheng; Luan, Xinjun] Northwest Univ, Coll Chem & Mat Sci, Key Lab Synthet & Nat Funct Mol, Minist Educ, Xian 710127, Peoples R China; [Lumb, Jean-Philip] McGill Univ, Dept Chem, Montreal, PQ H3A 0B8, Canada in 2020, Cited 55. SDS of cas: 93-97-0. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0
Polyfunctional arenes are an important part of the chemical value chain. To improve the efficiency of their synthesis, we have investigated a multicomponent approach built upon the Catellani platform. Here, we describe a 4-component coupling of aryl iodides lacking an ortho substituent that installs 3 discrete functional groups on the arene in a single step. The process is regio- and chemoselective and uncovers remote substituent effects that have a pronounced influence over inter mediate Pd-(II) complexes. These intermediates have been a long-standing focus of the Catellani-reaction development, but persistent challenges have given rise to the well-known ortho effect. We now show that the ortho effect can be a positive element of reaction design, and that previously problematic iodides can now be used in complexity-generating transformations. In expanding the scope of the Catellani platform, we hope to provide mechanistic considerations to guide future reaction design, while also improving the environmental footprint of synthesizing polyfunctional arenes.
SDS of cas: 93-97-0. Bye, fridends, I hope you can learn more about C14H10O3, If you have any questions, you can browse other blog as well. See you lster.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com