I found the field of Chemistry; Pharmacology & Pharmacy very interesting. Saw the article Synthesis and bioactivities of diamide derivatives containing a phenazine-1-carboxamide scaffold published in 2019.0. Product Details of 99-04-7, Reprint Addresses Du, XY; Wu, QL; Li, JK (corresponding author), Yangtze Univ, Sch Agr, Jingzhou, Peoples R China.; Wu, QL (corresponding author), Yangtze Univ, Minist Educ, Engn Res Ctr Ecol & Agr Use Wetland, Jingzhou, Peoples R China.; Li, JK (corresponding author), Yangtze Univ, Hubei Collaborat Innovat Ctr Grain Ind, Jingzhou, Peoples R China.. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid
Taking natural product phenazine-1-carboxamide (PCN) as a lead compound, a series of novel phenazine-1-carboxylic acid diamide derivatives were designed and synthesised. Their structures were confirmed by H-1-NMR and HRMS. The bioassays showed that some of the target compounds exhibited promising in vitro fungicidal activities, and exhibited excellent and selective herbicidal activities. Particularly, compounds c, h, o and s displayed root length inhibition activities against barnyard grass with the rate of more than 80%. Compound c exhibited the best activity among all the target compounds against barnyard grass stalk length with the IC50 value of 0.158 mmol/L, and compound o exhibited the best and wide spectrum inhibition against barnyard grass root length and rape in both root length and stalk length herbicidal activities with its IC50 values of 0.067, 0.048 and 0.059 mmol/L respectively. The analysis of preliminary Structure-Activity Relationships provides the theoretical basis for further design of phenazine-1-carboxylic acid. [GRAPHICS] .
About 3-Methylbenzoic acid, If you have any questions, you can contact Zhu, X; Zhang, M; Yu, LH; Xu, ZH; Yang, D; Du, XY; Wu, QL; Li, JK or concate me.. Product Details of 99-04-7
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com