An article A Dual Killing Strategy: Photocatalytic Generation of Singlet Oxygen with Concomitant Pt-IV Prodrug Activation WOS:000484178700001 published article about PHOTODYNAMIC THERAPY; 5-AMINOLEVULINIC ACID; CANCER-CELLS; OXALIPLATIN; REDUCTION; COMPLEXES; LIGANDS; AGENTS in [Norman, Daniel J.; Gambardella, Alessia; Mount, Andrew R.; Bradley, Mark] Univ Edinburgh, EaStChem Sch Chem, David Brewster Rd, Edinburgh, Midlothian, Scotland; [Murray, Alan F.] Univ Edinburgh, Sch Engn, Mayfield Rd, Edinburgh, Midlothian, Scotland in 2019, Cited 30. Recommanded Product: Benzoic anhydride. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0
A ruthenium-based mitochondrial-targeting photosensitiser that undergoes efficient cell uptake, enables the rapid catalytic conversion of Pt-IV prodrugs into their active Pt-II counterparts, and drives the generation of singlet oxygen was designed. This dual mode of action drives two orthogonal cancer-cell killing mechanisms with temporal and spatial control. The designed photosensitiser was shown to elicit cell death of a panel of cancer cell lines including those showing oxaliplatin-resistance.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com