Category: isothiazole. I found the field of Chemistry very interesting. Saw the article Rapid Deoxyfluorination of Alcohols with N-Tosyl-4-chlorobenzenesulfonimidoyl Fluoride (SulfoxFluor) at Room Temperature published in 2019, Reprint Addresses Ni, CF; Hu, JB (corresponding author), Univ Chinese Acad Sci, Chinese Acad Sci, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem,Key Lab Organofluorine C, 345 Ling Ling Rd, Shanghai 200032, Peoples R China.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride.
The deoxyfluorination of alcohols is a fundamentally important approach to access alkyl fluorides, and thus the development of shelf-stable, easy-to-handle, fluorine-economical, and highly selective deoxyfluorination reagents is highly desired. This work describes the development of a crystalline compound, N-tosyl-4-chlorobenzenesulfonimidoyl fluoride (SulfoxFluor), as a novel deoxyfluorination reagent that possesses all of the aforementioned merits, which is rare in the arena of deoxyfluorination. Endowed by the multi-dimensional modulating ability of the sulfonimidoyl group, SulfoxFluor is superior to 2-pyridinesulfonyl fluoride (PyFluor) in fluorination rate, and is also superior to perfluorobutanesulfonyl fluoride (PBSF) in fluorine-economy. Its reaction with alcohols not only tolerates a wide range of functionalities including the more sterically hindered alcoholic hydroxyl groups, but also exhibits high fluorination/elimination selectivity. Because SulfoxFluor can be easily prepared from inexpensive materials and can be safely handled without special techniques, it promises to serve as a practical deoxyfluorination reagent for the synthesis of various alkyl fluorides.
Category: isothiazole. About Benzoic anhydride, If you have any questions, you can contact Guo, JK; Kuang, CW; Rong, J; Li, LC; Ni, CF; Hu, JB or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com