Recommanded Product: 99-04-7. I found the field of Chemistry very interesting. Saw the article Ruthenium(II)-Catalyzed Hydrogen Isotope Exchange of Pharmaceutical Drugs by C-H Deuteration and C-H Tritiation published in 2020.0, Reprint Addresses Ackermann, L (corresponding author), Georg August Univ Gottingen, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany.. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid.
Well-defined ruthenium(II) biscarboxylate complexes enabled selective ortho-deuteration with weakly-coordinating, synthetically useful carboxylic acid with outstanding levels of isotopic labeling. The robust nature of the catalytic system was reflected by a broad functional group tolerance in an operationally-simple manner, allowing the isotope labeling of challenging pharmaceuticals and bioactive heterocyclic motifs. The synthetic power of our method was highlighted by the selective tritium-labeling of repaglinide, an antidiabetic drug, providing access to defined tritium labeled therapeutics.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com