An article Synthetic hyperacetylation of nucleosomal histones WOS:000616560700002 published article about CHROMATIN; COMPLEX; DISSOCIATION; CONSTANTS; PROTEINS in [Kajino, Hidetoshi; Oi, Miku; Yamatsugu, Kenzo; Kawashima, Shigehiro A.; Kanai, Motomu] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan; [Nagatani, Tomomi; Nishiyama, Atsuya; Nakanishi, Makoto] Univ Tokyo, Div Canc Cell Biol, Inst Med Sci, Minato Ku, 4-6-1 Shiroganedai, Tokyo 1088639, Japan; [Kujirai, Tomoya; Kurumizaka, Hitoshi] Univ Tokyo, Inst Quantitat Biosci, Bunkyo Ku, 1-1-1 Yayoi, Tokyo 1130032, Japan; [Kujirai, Tomoya; Kurumizaka, Hitoshi] KURUMIZAKA Chromatin Atlas, JST ERATO, Bunkyo Ku, 1-1-1 Yayoi, Tokyo 1130032, Japan in 2020, Cited 20. Application In Synthesis of Benzoic anhydride. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0
We report combinations of a DMAP-based catalyst and phenyl acetate with optimal electron density as a new chemical system for high-yield, selective synthetic acetylation of histone lysine residues. The utility of this chemical system as a unique biologic tool is demonstrated by applying it to Xenopus laevis sperm chromatin.
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