Mokrov, GV; Likhosherstov, AM; Barchukov, VV; Stolyaruk, VN; Tsorin, IB; Vititnova, MB; Kryzhanovskii, SA; Gudasheva, TA; Seredenin, SB in [Mokrov, G., V; Likhosherstov, A. M.; Barchukov, V. V.; Stolyaruk, V. N.; Tsorin, I. B.; Vititnova, M. B.; Kryzhanovskii, S. A.; Gudasheva, T. A.; Seredenin, S. B.] VV Zakusov State Inst Pharmacol, 8 Baltiiskaya St, Moscow 125315, Russia published Synthesis and Cardiotropic Activity of Linear Methoxyphenyltriazaalkanes in 2019.0, Cited 23.0. Recommanded Product: 2,5-Dimethoxybenzaldehyde. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.
A new group of potential pFOX inhibitors among linear methoxyphenyltriazaalkanes were designed and synthesized. Cardiotropic activity in rodent experiments was found for most of the synthesized compounds. The most active compound N-1-(2,3,4-trimethoxybenzyl)-N-2-{2-[(2,3,4-trimethoxybenzyl)amino]ethyl}-1,2-ethanediamine trihydrochloride (LM-1) combined anti-ischemic, antiarrhythmic, and antifibrillatory activities (1 mg/kg, i.v.) and low toxicity (LD50 = 119 mg/kg, mice, i.p.) and was selected for development as a potential cardiotropic drug.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com