In 2021 ANGEW CHEM INT EDIT published article about HYDROGEN-ATOM TRANSFER; DIRECT C-H; TRANSITION-METALS; DIRECT CONVERSION; METHYL ARENES; ALCOHOLS; FUNCTIONALIZATION; ALKYLATION; ARYLATION; ALDEHYDES in [Murugesan, Kathiravan; Donabauer, Karsten; Konig, Burkhard] Univ Regensburg, Fac Chem & Pharm, Regensburg, Germany in 2021, Cited 90. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. Recommanded Product: 3-Methylbenzoic acid
The metal-free activation of C(sp(3))-H bonds to value-added products is of paramount importance in organic synthesis. We report the use of the commercially available organic dye 2,4,6-triphenylpyrylium tetrafluoroborate (TPP) for the conversion of methylarenes to the corresponding aryl nitriles via a photocatalytic process. Applying this methodology, a variety of cyanobenzenes have been synthesized in good to excellent yield under metal- and cyanide-free conditions. We demonstrate the scope of the method with over 50 examples including late-stage functionalization of drug molecules (celecoxib) and complex structures such as l-menthol, amino acids, and cholesterol derivatives. Furthermore, the presented synthetic protocol is applicable for gram-scale reactions. In addition to methylarenes, selected examples for the cyanation of aldehydes, alcohols and oximes are demonstrated as well. Detailed mechanistic investigations have been carried out using time-resolved luminescence quenching studies, control experiments, and NMR spectroscopy as well as kinetic studies, all supporting the proposed catalytic cycle.
Bye, fridends, I hope you can learn more about C8H8O2, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 3-Methylbenzoic acid
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com