Recently I am researching about PHOTODYNAMIC THERAPY; 5-AMINOLEVULINIC ACID; CANCER-CELLS; OXALIPLATIN; REDUCTION; COMPLEXES; LIGANDS; AGENTS, Saw an article supported by the University of Edinburgh; UK Engineering and Physical Sciences Research Council through the Implantable Microsystems for Personalised Anti-Cancer Therapy (IMPACT) programme grantUK Research & Innovation (UKRI)Engineering & Physical Sciences Research Council (EPSRC) [EPK034510/1]. COA of Formula: C14H10O3. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Norman, DJ; Gambardella, A; Mount, AR; Murray, AF; Bradley, M. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
A ruthenium-based mitochondrial-targeting photosensitiser that undergoes efficient cell uptake, enables the rapid catalytic conversion of Pt-IV prodrugs into their active Pt-II counterparts, and drives the generation of singlet oxygen was designed. This dual mode of action drives two orthogonal cancer-cell killing mechanisms with temporal and spatial control. The designed photosensitiser was shown to elicit cell death of a panel of cancer cell lines including those showing oxaliplatin-resistance.
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Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com