I found the field of Chemistry very interesting. Saw the article Anti-tumor platinum (IV) complexes bearing the anti-inflammatory drug naproxen in the axial position published in 2019. Quality Control of Benzoic anhydride, Reprint Addresses Tolan, DA (corresponding author), Menoufia Univ, Dept Chem, Fac Sci, Shibin Al Kawm, Egypt.. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
The role of inflammation in cancer generation is gaining importance in the field of cancer research. The chemo-anti-inflammatory strategy that involves using non-steroidal anti-inflammatory drug compounds as effective anti-tumor agents is being acceded globally. In the present study, seven new Pt (IV) complexes based on cisplatin, carboplatin and oxaliplatin scaffold bearing the anti-inflammatory drug naproxen in the axial position were synthesized and characterized by elemental analysis, ESI-MS, Fourier transform-infrared, H-1- and Pt-195-NMR spectroscopy. The reduction behavior in the presence of ascorbic acid was studied using high-performance liquid chromatography. The cytotoxicity against two human breast cell lines and the anti-inflammatory properties were evaluated. All the complexes are able to promote a comparable activity, with average three- and 13-fold more cytotoxic than cisplatin against MCF7 and MDA-MB-231 cell lines, respectively. The complexes show remarkable anti-inflammatory effects, which indicated their potential in treating cancer associated with inflammation and reducing side-effects of chemotherapy.
Quality Control of Benzoic anhydride. Welcome to talk about 93-97-0, If you have any questions, you can contact Tolan, DA; Abdel-Monem, YK; El-Nagar, MA or send Email.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com