Application In Synthesis of 2,5-Dimethoxybenzaldehyde. In 2019.0 J AM CHEM SOC published article about CARBON QUATERNARY STEREOCENTERS; 6+3 CYCLOADDITION; MESO COMPOUNDS; GENERATION; CONSTRUCTION; PRESSURE; SULFUR; DENDRALENES; THIOPHENES; SULFONIUM in [Haut, Franz-Lucas; Habiger, Christoph; Muller, Thomas; Magauer, Thomas] Leopold Franzens Univ Innsbruck, Inst Organ Chem, Innrain 80-82, A-6020 Innsbruck, Austria; [Haut, Franz-Lucas; Habiger, Christoph; Muller, Thomas; Magauer, Thomas] Leopold Franzens Univ Innsbruck, Ctr Mol Biosci, Innrain 80-82, A-6020 Innsbruck, Austria; [Speck, Klaus; Mayer, Peter; Korber, Johannes Nepomuk] Ludwig Maximilians Univ Munchen, Dept Chem & Pharm, Butenandtstr 5-13, D-81377 Munich, Germany; [Wurst, Klaus] Leopold Franzens Univ Innsbruck, Inst Gen Inorgan & Theoret Chem, Innrain 80-82, A-6020 Innsbruck, Austria in 2019.0, Cited 63.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7.
Here we present a comprehensive study on the [3+2]-cycloaddition of thiocarbonyl ylides with a wide variety of alkenes and alkynes. The obtained dihydro- and tetrahydrothiophene products serve as exceptionally versatile intermediates providing access to thiophenes, dienes, dendralenes, and vic-quarternary carbon centers. The use of high-pressure conditions enables thermally unstable, sterically encumbered or moderately reactive substrates to undergo the cycloaddition under mild conditions, thereby increasing the yield by up to 58%. In addition, we showcase its utility by the formal syntheses of the pharmaceuticals NGB 4420 and tenilapine.
About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Haut, FL; Habiger, C; Speck, K; Wurst, K; Mayer, P; Korber, JN; Muller, T; Magauer, T or concate me.. Application In Synthesis of 2,5-Dimethoxybenzaldehyde
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com