An article The Enantioselective Synthesis of Chiral Carbocyclic Nucleosides via Palladium-Catalyzed Asymmetric Allylic Amination of Alicyclic MBH Adducts with Purines WOS:000523235000001 published article about METHYLENECYCLOPROPANE ANALOGS; STEREOSELECTIVE-SYNTHESIS; ANTIVIRAL ACTIVITY; POTENT; DERIVATIVES; INHIBITOR; 1592U89; LIGAND in [Kang, Bo; Zhang, Qi-Ying; Qu, Gui-Rong; Guo, Hai-Ming] Henan Normal Univ, Henan Key Lab Organ Funct Mol & Drug Innovat, Key Lab Green Chem Media & React,Sch Chem & Chem, Minist Educ,Collaborat Innovat Ctr Henan Prov Gre, Xinxiang 453007, Henan, Peoples R China in 2020, Cited 40. SDS of cas: 93-97-0. The Name is Benzoic anhydride. Through research, I have a further understanding and discovery of 93-97-0
The enantioselective synthesis of carbocyclic nucleosides through the palladium-catalyzed asymmetric allylic amination of alicyclic Morita-Baylis-Hillman (MBH) adducts with purines was successfully developed. With a combination of Pd-2 (dba)(3)/L7 as catalyst, various optically active carbocyclic nucleosides featuring a C=C double bond in the carbocycle moiety were obtained in high yields (up to 97%) with excellent N-9/N-7-selectivities (> 95/5) and enantioselectivities (up to > 99.6%). In addition, these nucleoside analogs allowed for rapid transformation to a variety of other interesting structurally diverse chiral carbocyclic nucleosides.
SDS of cas: 93-97-0. Welcome to talk about 93-97-0, If you have any questions, you can contact Kang, B; Zhang, QY; Qu, GR; Guo, HM or send Email.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com