An article Weak Bases-Mediated Modified Favorskii Reaction-Type Direct Alkynylation/(E)-Alkenylation: A Unified Rapid Access to alpha,beta-Unsaturated Ketones and Propargyl Alcohols WOS:000498438500001 published article about CARBONYLATIVE HECK REACTIONS; CATALYTIC ALKYNYLATION; EFFICIENT SYNTHESIS; COUPLING REACTIONS; ALDEHYDES; CHALCONE; DERIVATIVES; HYDROXIDE; ALKYNES; ACIDS in [Tiwari, Mohit K.; Yadav, Lalit; Shyamlal, Bharti Rajesh Kumar; Chaudhary, Sandeep] Malaviya Natl Inst Technol Jaipur, Lab Organ & Med Chem, Dept Chem, Jawaharlal Nehru Marg, Jaipur 302017, Rajasthan, India in 2019.0, Cited 76.0. The Name is 2,5-Dimethoxybenzaldehyde. Through research, I have a further understanding and discovery of 93-02-7. Category: isothiazole
Herein, we report an unprecedented, fast, highly efficient, transition-metal-free, modified Favorskii reaction-type direct alkynylation and (E)-alkenylation protocol towards the synthesis of alpha,beta-unsaturated ketones and propargyl alcohols that proceeds using the combination of Cs2CO3 and Et3N as weak bases in up to 99% yields. In this reaction, aromatic aldehydes afforded alpha,beta-unsaturated ketones and aliphatic aldehydes furnished propargyl alcohols, respectively. A proposed mechanistic pathway illustrates the involvement of weak base-assisted propargylation of carbonyl compounds followed by allenol-enone tautomerism to furnish (E)-alkenylated product.
Category: isothiazole. About 2,5-Dimethoxybenzaldehyde, If you have any questions, you can contact Tiwari, MK; Yadav, L; Shyamlal, BRK; Chaudhary, S or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com