Recently I am researching about TERMINAL ARYL ALKENES; C-N; ANALOGS; CONDENSATION; DERIVATIVES; ACYLATION; C-SP3-H; ESTERS, Saw an article supported by the DST-NRF Indo-South Africa Joint research project [DST/INT/South Africa/P-19/2016]; DST, New DelhiDepartment of Science & Technology (India); UGC, New DelhiUniversity Grants Commission, India; MNIT Jaipur. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Sharma, R; Yadav, L; Yadav, RK; Chaudhary, S. The CAS is 93-02-7. Through research, I have a further understanding and discovery of 2,5-Dimethoxybenzaldehyde. Quality Control of 2,5-Dimethoxybenzaldehyde
An efficient, cost-effective, transition-metal-free, oxidative C-H cross-dehydrogenative coupling via a C-H bond functionalization protocol for the regioselective direct C-3 acylation/benzoylation of substituted 2H-Indazoles 1a-m with substituted aldehydes 2a-q/benzyl alcohols 5a-e/styrenes 6a-e is reported. The operationally simple protocol proceeds in the presence of tert-butyl peroxybenzoate (TBPB) as an oxidant in chlorobenzene (PhCl) as a solvent at 110 degrees C for 24 h under an inert atmosphere, which furnished a diverse variety of substituted 3-(acyl/benzoyl)-2H-indazoles 3a-q/4a-l in up to 87% yields. The reaction involves a free-radical mechanism and proceeds via the addition of an in situ generated acyl radical (from aldehydes/benzyl alcohols/styrenes) on 2H-indazoles. The functional group tolerance, broad substrate scope, control/competitive experiments and gram-scale synthesis and its application to the synthesis of anti-inflammatory agent 11 and novel indazole-fused diazepine 13 further signify the versatile nature of the developed methodology.
Quality Control of 2,5-Dimethoxybenzaldehyde. Welcome to talk about 93-02-7, If you have any questions, you can contact Sharma, R; Yadav, L; Yadav, RK; Chaudhary, S or send Email.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com