Formula: C8H8O2. I found the field of Chemistry very interesting. Saw the article Ru-Catalyzed (E)-Specific ortho-C-H Alkenylation of Arenecarboxylic Acids by Coupling with Alkenyl Bromides published in 2021, Reprint Addresses Goossen, LJ (corresponding author), Ruhr Univ Bochum, Evonik Chair Organ Chem, D-44801 Bochum, Germany.. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid.
In the presence of [p-cymene)RuCl2](2), (E)-configured alkenyl bromides couple with aromatic carboxylates to form orthovinylbenzoic acids. This C-H vinylation proceeds in high yields without any activating phosphine ligands and has an excellent functional group tolerance. Starting from commonly available (E/Z)-mixtures of alkenyl bromides, (E)-configured vinyl arenes or dienes are formed exclusively. Mechanistic studies show that this selectivity is achieved because the (E)configured alkenyl bromides undergo a smooth coupling, whereas the (Z)-isomers are rapidly eliminated with the formation of alkynes.
About 3-Methylbenzoic acid, If you have any questions, you can contact Hu, ZY; Belitz, F; Zhang, GD; Papp, F; Goossen, LJ or concate me.. Formula: C8H8O2
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com