Formula: C8H8O2. In 2021.0 RSC ADV published article about ESTERS; ACID; MECHANOCHEMISTRY; ULTRASOUND; CHALLENGES; MICROWAVE; MITSUNOBU; REAGENT; OIL in [Zheng, Lei; Sun, Chen; Xu, Wenhao; Su, Weike] Zhejiang Univ Technol, Key Lab Green Pharmaceut Technol & Related Equipm, Minist Educ, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China; [Xu, Wenhao; Su, Weike; Yu, Jingbo] Zhejiang Univ Technol, Natl Engn Res Ctr Proc Dev Act Pharmaceut Ingredi, Collaborat Innovat Ctr Yangtze River Delta Reg Gr, Hangzhou 310014, Peoples R China; [Dushkin, Alexandr V.; Polyakov, Nikolay] Inst Solid State Chem & Mechanochem, Novosibirsk, Russia in 2021.0, Cited 55.0. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.
Herein, we describe two novel strategies for the synthesis of esters, as achieved under high-speed ball-milling (HSBM) conditions at room temperature. In the presence of I-2 and KH2PO2, the reactions afford the desired esterification derivatives in 45% to 91% yields within 20 min of grinding. Meanwhile, using KI and P(OEt)(3), esterification products can be obtained in 24% to 85% yields after 60 min of grinding. In addition, the I-2/KH2PO2 protocol was successfully extended to the late-stage diversification of natural products showing the robustness of this useful approach. Further application of this method in the synthesis of inositol nicotinate was also discussed.
About 3-Methylbenzoic acid, If you have any questions, you can contact Zheng, L; Sun, C; Xu, WH; Dushkin, AV; Polyakov, N; Su, WK; Yu, JB or concate me.. Formula: C8H8O2
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com