Recently I am researching about TRANSPOSON MUTANT LIBRARY; PYOCYANIN; SEQUENCE; MUCOIDY; PROBES; ALGP, Saw an article supported by the Deutsche ForschungsgemeinschaftGerman Research Foundation (DFG) [SI-1096/10-1, WI3285/61]; National Science FoundationNational Science Foundation (NSF) [CHE1755698]; National Institute of General Medical SciencesUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [GM119426]; Cystic Fibrosis FoundationItalian Cystic Fibrosis Research Foundation [MCCART15R0]; NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of Allergy & Infectious Diseases (NIAID) [R21AI122192, F31AI136310] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) – USANIH National Institute of General Medical Sciences (NIGMS) [R35GM119426] Funding Source: NIH RePORTER. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Zhao, WN; Cross, AR; Crowe-McAuliffe, C; Weigert-Munoz, A; Csatary, EE; Solinski, AE; Krysiak, J; Goldberg, JB; Wilson, DN; Medina, E; Wuest, WM; Sieber, SA. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene. Application In Synthesis of 1,3-Dimethoxybenzene
Natural products represent a rich source of antibiotics that address versatile cellular targets. The deconvolution of their targets via chemical proteomics is often challenged by the introduction of large photocrosslinkers. Here we applied elegaphenone, a largely uncharacterized natural product antibiotic bearing a native benzophenone core scaffold, for affinity-based protein profiling (AfBPP) in Gram-positive and Gram-negative bacteria. This study utilizes the alkynylated natural product scaffold as a probe to uncover intriguing biological interactions with the transcriptional regulator AlgP. Furthermore, proteome profiling of a Pseudomonas aeruginosa AlgP transposon mutant provided unique insights into the mode of action. Elegaphenone enhanced the elimination of intracellular P.aeruginosa in macrophages exposed to sub-inhibitory concentrations of the fluoroquinolone antibiotic norfloxacin.
Application In Synthesis of 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Zhao, WN; Cross, AR; Crowe-McAuliffe, C; Weigert-Munoz, A; Csatary, EE; Solinski, AE; Krysiak, J; Goldberg, JB; Wilson, DN; Medina, E; Wuest, WM; Sieber, SA or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com