Recommanded Product: 1,3-Dimethoxybenzene. Recently I am researching about TRANSFER RADICAL-ADDITION; LIGHT; CYCLIZATION; HALIDES; ALKYLATION; REDUCTION; YNAMIDES; LUOTONIN, Saw an article supported by the Universite libre de Bruxelles (ULB); Federation Wallonie-Bruxelles (ARC Consolidator 2014-2019); COST actionEuropean Cooperation in Science and Technology (COST) [CM1202]; Fonds pour la formation a la Recherche dans l’Industrie et dans l’Agriculture (F.R.I.A.)Fonds de la Recherche Scientifique – FNRS; Fonds de la Recherche Scientifique (FNRS)Fonds de la Recherche Scientifique – FNRS; Innoviris (project PhotoCop). Published in JOURNAL OF VISUALIZED EXPERIMENTS in CAMBRIDGE ,Authors: Baguia, H; Deldaele, C; Michelet, B; Beaudelot, J; Theunissen, C; Moucheron, C; Evano, G. The CAS is 151-10-0. Through research, I have a further understanding and discovery of 1,3-Dimethoxybenzene
Our group recently reported the use of [(DPEPhos)(bcp)Cu]PF6 as a general copper-based photoredox catalyst which proved efficient to promote the activation of a broad variety of organic halides, including unactivated ones. These can then participate in various radical transformations such as reduction and cyclization reactions, as well as in the direct arylation of several (hetero)arenes. These transformations provide a straightforward access to a range of small molecules of interest in synthetic chemistry, as well as to biologically active natural products. Altogether, [(DPEPhos)(bcp)Cu]PF6 acts as a convenient photoredox catalyst which appears to be an attractive, cheap and complementary alternative to the state-of-the-art iridium- and ruthenium-based photoredox catalysts. Here, we report a detailed protocol for the synthesis of [(DPEPhos)(bcp)Cu]PF6, as well as NMR and spectroscopic characterizations, and we illustrate its use in synthetic chemistry for the direct arylation of (hetero)arenes and radical cyclization of organic halides. In particular, the direct arylation of N-methylpyrrole with 4-iodobenzonitrile to afford 4-(1-methyl-1H-pyrrol-2-yl)benzonitrile and the radical cyclization of N-benzoyl-N-[(2-iodoquinolin-3-yl)methyl]cyanamide to afford natural product luotonin A are detailed. The scope and limitations of this copper-based photoredox catalyst are also briefly discussed.
Recommanded Product: 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Baguia, H; Deldaele, C; Michelet, B; Beaudelot, J; Theunissen, C; Moucheron, C; Evano, G or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com