An article Cu-Mediated Amination of (Hetero)Aryl C-H bonds with NH Azaheterocycles WOS:000495334100001 published article about BIOLOGICAL EVALUATION; MEDICINAL CHEMISTS; FUNCTIONALIZATION; DERIVATIVES; ARENES; ARYL; INHIBITOR; CARBAZOLE; DISCOVERY; ARYLATION in [Yu, Jin-Feng; Li, Jian-Jun; Wang, Peng] Chinese Acad Sci, Shanghai Inst Organ Chem, Ctr Excellence Mol Synth, State Key Lab Organometall Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China; [Wang, Peng] Chinese Acad Sci, CAS Key Lab Energy Regulat Mat, Shanghai Inst Organ Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China; [Yu, Jin-Quan] Scripps Res Inst TSRI, 10550 North Torrey Pines Rd, La Jolla, CA 92037 USA in 2019.0, Cited 56.0. Computed Properties of C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7
Direct synthesis of N-(hetero)arylated heteroarenes has been realized through Cu-mediated C-N coupling of NH azaheterocycles with aryl C-H bonds under aerobic conditions. This method features a broad scope of both heterocyclic arenes (pyridine, quinoline, pyrazole, imidazole, furan, thiophene, benzofuran, and indole) and NH azaheterocycles (imidazole, pyrazole, indole, azindole, purine, indazole, benzimidazole, pyridone, carbazole), providing a versatile method for the synthesis of pharmaceutically important N-(hetero)arylated heteroarenes. The versatility of this reaction was further demonstrated through late-stage modification of marketed drugs and the synthesis of a key intermediate for accessing a class of angiotensin II receptor 1 antagonists.
Computed Properties of C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact Yu, JF; Li, JJ; Wang, P; Yu, JQ or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com