Kadam, AA; Metz, TL; Qian, YQ; Stanley, LM in [Kadam, Abhishek A.; Metz, Tanner L.; Qian, Yiqiu; Stanley, Levi M.] Iowa State Univ, Dept Chem, Ames, IA 50011 USA published Ni-Catalyzed Three-Component Alkene Carboacylation Initiated by Amide C-N Bond Activation in 2019, Cited 45. COA of Formula: C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7.
The nickel-catalyzed intermolecular carboacylation of alkenes with amides and tetraarylborates is presented. Bicyclic alkenes are readily functionalized with a variety of N-benzoyl-N-phenylbenzamides and triarylboranes, which are generated in situ from the corresponding tetraarylborates, to synthesize ketone products in up to 91% yield. Preliminary mechanistic studies suggest that migratory insertion precedes transmetalation and that reductive elimination is the turnover-limiting step. These reactions occur with excellent chemoselectivity and diastereoselectivity in the absence of a directing/chelating group and further demonstrate amides as practical acyl electrophiles for alkene dicarbofunctionalization reactions.
COA of Formula: C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact Kadam, AA; Metz, TL; Qian, YQ; Stanley, LM or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com