I found the field of Chemistry very interesting. Saw the article Palladium-Catalyzed N-Acylation of Tertiary Amines by Carboxylic Acids: A Method for the Synthesis of Amides published in 2020. Application In Synthesis of 3-Methylbenzoic acid, Reprint Addresses Chen, TQ (corresponding author), Hainan Univ, Hainan Prov Fine Chem Engn Res Ctr, Hainan Prov Key Lab Fine Chem, Key Lab,Minist Educ Adv Mat Trop Isl Resources, Haikou 570228, Hainan, Peoples R China.. The CAS is 99-04-7. Through research, I have a further understanding and discovery of 3-Methylbenzoic acid
A palladium-catalyzed N-acylation of tertiary amines by carboxylic acids was achieved through C-N cleavage. This reaction showed a wide substrate scope. Both aromatic and aliphatic acids served well as the acylating reagents and coupled with tertiary amines to produce the corresponding amides in good to excellent yields. With the strategy, bioactive carboxylic acids were also efficiently modified, highlighting the synthetic value of the process in organic synthesis.
About 3-Methylbenzoic acid, If you have any questions, you can contact Li, ZH; Liu, L; Xu, KQ; Huang, TZ; Li, XY; Song, B; Chen, TQ or concate me.. Application In Synthesis of 3-Methylbenzoic acid
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com