An article Synthesis of Triazolo- and Oxadiazolopiperazines by Gold(I)-Catalyzed Domino Cyclization: Application to the Design of a Mitogen Activated Protein (MAP) Kinase Inhibitor WOS:000456633000006 published article about CATALYZED INTRAMOLECULAR HYDROAMINATION; PATHWAY DEPENDENT MALIGNANCIES; POTENT SMOOTHENED ANTAGONIST; FUSED PIPERAZINE; INTERMOLECULAR HYDROAMINATION; NEUROKININ-3 RECEPTOR; UNACTIVATED ALKENES; RAPID ACCESS; DERIVATIVES; ALKYNES in [Yamamoto, Koki; Inuki, Shinsuke; Ohno, Hiroaki; Oishi, Shinya] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto 6068501, Japan; [Yoshikawa, Yasushi; Ohue, Masahito] Tokyo Inst Technol, Sch Comp, Dept Comp Sci, Meguro Ku, Tokyo 1528550, Japan in 2019, Cited 58. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7. SDS of cas: 99-04-7
An efficient method for the synthesis of [1,2,4]triazolo-[4,3-a]piperazine derivatives was established based on a gold(I)-catalyzed domino cyclization of an amidrazone substrate with a terminal alkyne. The amidoxime congeners were converted into [1,2,4]oxadiazolo[4,5-a]piperazine derivatives in the presence of a gold catalyst. The oxadiazolopiperazine is a promising scaffold for the design of novel inhibitors against p38 mitogen activated protein kinase (MAP kinase).
About 3-Methylbenzoic acid, If you have any questions, you can contact Yamamoto, K; Yoshikawa, Y; Ohue, M; Inuki, S; Ohno, H; Oishi, S or concate me.. SDS of cas: 99-04-7
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com