Name: Benzoic anhydride. Recently I am researching about PALLADIUM-CATALYZED ALKYLATION; C-H FUNCTIONALIZATION; ARYL IODIDES; ROUTE; PD/NORBORNENE; HETEROCYCLES; ARYLATION; ACYLATION; ACYLATION/ALKENYLATION; EFFICIENT, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21925108]; Key Science and Technology Innovation Team of Shaanxi [2017KCT-37]; Key Laboratory Project of Xi’an [201805058ZD9CG42]. Published in CELL PRESS in CAMBRIDGE ,Authors: Wang, J; Qin, C; Lumb, JP; Luan, XJ. The CAS is 93-97-0. Through research, I have a further understanding and discovery of Benzoic anhydride
Polyfunctional arenes are an important part of the chemical value chain. To improve the efficiency of their synthesis, we have investigated a multicomponent approach built upon the Catellani platform. Here, we describe a 4-component coupling of aryl iodides lacking an ortho substituent that installs 3 discrete functional groups on the arene in a single step. The process is regio- and chemoselective and uncovers remote substituent effects that have a pronounced influence over inter mediate Pd-(II) complexes. These intermediates have been a long-standing focus of the Catellani-reaction development, but persistent challenges have given rise to the well-known ortho effect. We now show that the ortho effect can be a positive element of reaction design, and that previously problematic iodides can now be used in complexity-generating transformations. In expanding the scope of the Catellani platform, we hope to provide mechanistic considerations to guide future reaction design, while also improving the environmental footprint of synthesizing polyfunctional arenes.
About Benzoic anhydride, If you have any questions, you can contact Wang, J; Qin, C; Lumb, JP; Luan, XJ or concate me.. Name: Benzoic anhydride
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com