Authors He, Y; Liao, XZ; Dong, L; Chen, FE in ROYAL SOC CHEMISTRY published article about C-H FUNCTIONALIZATION; BOND FORMATION; NITRATED INDENOISOQUINOLINES; INTERNAL ALKYNES; ACTIVATION; INSERTION; COBALT; PHENYLAZOLES; CYCLIZATION; MULTIPLE in [He, Yuan; Liao, Xian-Zhang; Dong, Lin; Chen, Fen-Er] Sichuan Univ, West China Sch Pharm, Minist Educ, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Peoples R China; [Chen, Fen-Er] Fudan Univ, Dept Chem, Engn Ctr Catalysis & Synth Chiral Mol, Shanghai 200433, Peoples R China; [Chen, Fen-Er] Shanghai Engn Ctr Ind Asymmetr Catalysis Chiral D, Shanghai 200433, Peoples R China in 2021.0, Cited 74.0. HPLC of Formula: C8H8O2. The Name is 3-Methylbenzoic acid. Through research, I have a further understanding and discovery of 99-04-7
Developing powerful methods to introduce versatile functional groups at the N-substituents of isoquinolone scaffolds is still a great challenge. Herein, we report a novel three-component cascade annulation reaction to efficiently construct the N-oxopropyl chain of isoquinolone derivatives via rhodium(iii)-catalyzed C-H activation/cyclization/nucleophilic attack, with oxazoles used both as the directing group and potential functionalized reagents.
HPLC of Formula: C8H8O2. About 3-Methylbenzoic acid, If you have any questions, you can contact He, Y; Liao, XZ; Dong, L; Chen, FE or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com