Safety of 1,3-Dimethoxybenzene. In 2019 ORG LETT published article about REDOX-ACTIVE ESTERS; RING-OPENING TRIFLUOROMETHYLATION; BOND-FORMING REACTIONS; ZINC-HOMOENOLATE; C-C; KETONES; ALPHA in [Mills, L. Reginald; Zhou, Cuihan; Fung, Emily; Rousseaux, Sophie A. L.] Univ Toronto, Dept Chem, Davenport Res Labs, 80 St George St, Toronto, ON M5S 3H6, Canada; [Zhou, Cuihan] McGill Univ, Dept Chem, 801 Sherbrooke St West, Montreal, PQ H3A 0B8, Canada in 2019, Cited 35. The Name is 1,3-Dimethoxybenzene. Through research, I have a further understanding and discovery of 151-10-0.
Metal homoenolates are valuable synthetic intermediates which provide access to beta-functionalized ketones. In this report, we disclose a Ni-catalyzed beta-alkylation reaction of cyclopropanol-derived homoenolates using redox-active N-hydroxyphthalimide (NHPI) esters as the alkylating reagents. The reaction is compatible with 1 degrees, 2 degrees, and 3 degrees NHPI esters. Mechanistic studies imply radical activation of the NHPI ester and 2e beta-carbon elimination occurring on the cyclopropanol.
Safety of 1,3-Dimethoxybenzene. About 1,3-Dimethoxybenzene, If you have any questions, you can contact Mills, LR; Zhou, CH; Fung, E; Rousseaux, SAL or concate me.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com