New discoveries in chemical research and development in 2021, Chemistry involves the study of all things chemical – chemical processes, how they change and how they react in certain situations. 385-00-2, Name is 2,6-Difluorobenzoic acid, SMILES is O=C(O)C1=C(F)C=CC=C1F, in an article , author is Omelian, Taras, V, once mentioned of 385-00-2, Application of 385-00-2.
We report a strategy for the construction of tetrahydro-1H-1(6)-pyrrolo[1,2-b]isothiazole-1,1,3(2H)-triones bearing the substituents at the 5- and/or 3a-positions. To this purpose, a range of 2-substituted and 2,4-disubstituted methyl 2-pyrrolidinecarboxylates were sulfonylated with methanesulfonyl chloride and the resulting sulfonamides were subjected to sulfa-Dieckmann condensation through the CSIC (Carbanion mediated Sulfonate (Sulfonamido) Intramolecular Cyclization) reaction to give the desired 1(6)-isothiazolidine-1,1,4-triones. All the precursors, as well as target compounds, could be synthesized in a multigram scale following the general protocols.
Application of 385-00-2, Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. I hope my blog about 385-00-2 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com