Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation.3218-36-8, Name is [1,1′-Biphenyl]-4-carbaldehyde, molecular formula is C13H10O, belongs to isothiazole compound. In a document, author is Clerici, F, introduce the new discover, Synthetic Route of 3218-36-8.
3-Diethylamino-4-(4-methoxyphenyl)-5-vinyl-isothiazole 1,1-dioxide was reacted with nitrile oxides and munchnones affording the cycloadducts in good yields. The cycloaddition reaction occurred at the vinyl group exclusively. The cycloadducts undergo pyrolytic transformation into alpha,beta-unsaturated nitriles through the isoxazole- or pyrrole-isothiazoline 1,1-dioxide intermediates. (C) 1998 Elsevier Science Ltd. All rights reserved.
Synthetic Route of 3218-36-8, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect. I hope my blog about 3218-36-8 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com