Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 827-25-8, Name is 2-Bromo-4-chloro-6-nitrophenylamine, molecular formula is C6H4BrClN2O2, belongs to isothiazole compound. In a document, author is Ryan, Sarah J., introduce the new discover, Quality Control of 2-Bromo-4-chloro-6-nitrophenylamine.
N-aryl methylene benzo-fused sultams (2,3-dihydrobenzo[d]isothiazole 1,1-dioxides) underwent [3+2] cycloaddition with benzonitrile oxide to give 5-spiro isoxazoline adducts with complete regioselectivity. Steric hindrance by atropisomerism around the N-aryl bond induced facial selectivity in these cycloadditions.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 827-25-8, Quality Control of 2-Bromo-4-chloro-6-nitrophenylamine.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com