Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 582-24-1, Name is 2-Hydroxy-1-phenylethanone, molecular formula is C8H8O2, SDS of cas: 582-24-1, belongs to isothiazole compound, is a common compound. In a patnet, author is Atobe, Masakazu, once mentioned the new application about 582-24-1.
A series of 1,1-dioxothieno[2,3-d]isothiazole (thienosultam) derivatives were designed and synthesized as novel ADAMTS-5 inhibitors for an investigation into a side chain of thienosultam for the S1′ pocket. The resulting compounds (19 and 24) show high ADAMTS-5 inhibition and other MMP selectivity, and these compounds show good oral bioavailability. (C) 2013 Elsevier Ltd. All rights reserved.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 582-24-1, SDS of cas: 582-24-1.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com