Chemistry involves the study of all things chemical – chemical processes, chemical compositions and chemical manipulation – in order to better understand the way in which materials are structured, how they change and how they react in certain situations. 99-04-7, Name is 3-Methylbenzoic acid, molecular formula is C8H8O2, belongs to isothiazole compound. In a document, author is Kletskov, Alexey, V, introduce the new discover, Synthetic Route of 99-04-7.
We report for the first time cyclic phosphine-free head to tail N,N,N pincer-like (pincer complexes mimicking) N-(pyrimidin-2-yl)-1,2-azole-3-carboxamide Pd(II) complexes with deprotonated amide groups as high-turnover catalysts (TON up to 10(6), TOF up to 1.2 x 10(7) h(-1)) for cross-coupling reactions on the background of up to quantitative yields under Green Chemistry conditions. The potency of the described catalyst family representatives was demonstrated in Suzuki-Miyaura, Mizoroki-Heck, and Sonogashira reactions on industrially practical examples. Corresponding ligands could be synthesized based on readily available reagents through simple chemical transformations. Within the complex structures, a highly unusual 1,3,5,7-tetraza-2,6-dipalladocane frame could be observed.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. In my other articles, you can also check out more blogs about 99-04-7. Synthetic Route of 99-04-7.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com