Extracurricular laboratory: Synthetic route of 87691-88-1

As the rapid development of chemical substances, we look forward to future research findings about 87691-88-1

3-Piperazinobenzisothiazole hydrochloride, cas is 87691-88-1, it is a common heterocyclic compound, the isothiazole compound, its synthesis route is as follows.,87691-88-1

The above intermediate IV (0.01 mol) and the hydrochloride salt of the piperazine compound (V) (0.01 mol) were dissolved in DMF (100 mL).In the middle, K2CO3 (0.02 mol) was added. 3-(4-(3-(5-methyl-1H-indol-3-yl)propyl)piperazine-1-yl)benzo[d]isothiazole (VI-8) hydrochloride (white solid) 3.20 g, yield 75%.

As the rapid development of chemical substances, we look forward to future research findings about 87691-88-1

Reference£º
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Gu Zhengsong; Zhou Ainan; Xiao Ying; (26 pag.)CN109467554; (2019); A;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com