Chemical Research Letters, April 2021. Healthcare careers for chemists are once again largely based in laboratories, although increasingly there is opportunity to work at the point of care, helping with patient investigation. 393-11-3, Name is 4-Nitro-3-(trifluoromethyl)aniline, molecular formula is C7H5F3N2O2, Safety of 4-Nitro-3-(trifluoromethyl)aniline, belongs to isothiazole compound, is a common compound. In a patnet, author is Barton, Peter, once mentioned the new application about 393-11-3.
A new synthesis of 3-amino-5-arylisothiazoles is reported. The reaction is operationally simple, utilises readily synthesised propynenitriles as starting materials and is tolerant of a range of functional groups. The optimised reaction conditions can also be used with 3-chloropropenenitriles in place of propynenitriles. (C) 2018 Elsevier Ltd. All rights reserved.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 393-11-3, Safety of 4-Nitro-3-(trifluoromethyl)aniline.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com