Chemical Research Letters, April 2021. Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 91-10-1, Name is 2,6-Dimethoxyphenol, molecular formula is C8H10O3, Application In Synthesis of 2,6-Dimethoxyphenol, belongs to isothiazole compound, is a common compound. In a patnet, author is Fisher, Matthew J., once mentioned the new application about 91-10-1.
The disclosed 3-phenyl-5-isothiazole carboxamides are potent allosteric antagonists of mGluR1 with generally good selectivity relative to the related group 1 receptor mGluR5. Pharmacokinetic properties of a member of this series (1R,2R)-N-(3-(4-methoxyphenyl)-4-methylisothiazol-5-yl)-2-methylcyclopropanecarboxamide (14) are good, showing acceptable plasma and brain exposure after oral dosing. Oral administration of isothiazole 14 gave robust activity in the formalin model of persistent pain which correlated with CNS receptor occupancy. (C) 2012 Elsevier Ltd. All rights reserved.
Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield. If you are hungry for even more, make sure to check my other article about 91-10-1, Application In Synthesis of 2,6-Dimethoxyphenol.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com