Chemical Research Letters, April 2021. Chemical engineers ensure the efficiency and safety of chemical processes, adapt the chemical make-up of products to meet environmental or economic needs, and apply new technologies to improve existing processes. 1583-58-0, Name is 2,4-Difluorobenzoic acid, molecular formula is C7H4F2O2, Application of 1583-58-0, belongs to isothiazole compound, is a common compound. In a patnet, author is Matzen, L, once mentioned the new application about 1583-58-0.
The AMPA receptor agonist Thio-AMPA, the 3-isothiazolol analogue of AMPA was converted into the selective NMDA antagonist, 2, in which a 3-isothiazolone unit is a bioisosteric analogue of the peptide bond of the NMDA antagonist, gamma-(R)-Glu-Gly. The isomeric 3-oxygenated isothiazole amino acid, 3, and the corresponding isothiazole phosphono amino acid 4 were also synthesized, and were shown to be selective AMPA receptor antagonists. Compound 1, in which the peptide bond of gamma-(R)-Glu-Gly is replaced by an ester group, was synthesized and shown to be unstable in the test buffer system. (C) 1997 Elsevier Science Ltd.
Application of 1583-58-0, Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. I hope my blog about 1583-58-0 is helpful to your research.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com