New Advances in Chemical Research in 2021, Chemistry graduates have much scope to use their knowledge in a range of research sectors, including roles within chemical engineering, chemical and related industries, healthcare and more. 103-60-6, Name is 2-Phenoxyethyl isobutyrate, molecular formula is C12H16O3, belongs to isothiazole compound. In a document, author is MALLERON, JL, introduce the new discover, Quality Control of 2-Phenoxyethyl isobutyrate.
A series of 2-(aminoalkyl)naphth[1,8-cd]isothiazole 1,1-dioxides was synthesized and examined in various receptor binding tests. Most compounds demonstrated high affinity for the 5-HT2 receptor with moderate to high selectivity. A member of this series, compound 24 (RP 62203), displays high 5-HT2 receptor affinity (K(i) = 0.26 nM), which is respectively more than 100 and 1000 times higher than its affinity for alpha-1 (K(i) = 38 nM) and D2 (K(i) > 1000 nM) receptors. This compound is a potent orally effective and long lasting 5-HT2 antagonist in the mescaline-induced head-twitches test in mice and rats.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 103-60-6, Quality Control of 2-Phenoxyethyl isobutyrate.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com