27148-03-4, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide, cas is 27148-03-4,the isothiazole compound, it is a common compound, a new synthetic route is introduced below.
The complex was synthesized by addition of 4,4′-trimethylenedipyridine (6.2 mg, 0.031 mmol) and thiosaccharine (12.7 mg, 0.0638 mmol), respectively, to a solution of Zn(NO3)26H2O (10.2mg, 0.0342 mmol) in ethanol:water (4 ml), and kept under mechanical stirring at room temperature. The resulting yellow solid was filtered off and washed with cold water. By slow evaporation of the mother solution single crystals appeared. They were washed with water and analysed using X-ray diffraction. Yield: 82%. Molar conductivity (mS M1) = 28.3. Analytical percent composition calculated for C27H22N4O4S4Zn: C = 49.127%; H = 3.359%;N = 8.487%. Found: C = 48.811%; H = 2.981%; N = 8.378%. Soluble in DMSO and DMF. Slightly soluble in water, ethanol, methanol, chloroform. Insoluble in acetone and methane dichloride. UV-Visible [DMSO, kmax nm]: 347.1H NMR (300 MHz, DMSO) d 8.46 (dd, 4H), 7.92 (m, 2H), 7.58-7.72 (m, 6H), 7.28 (dd, 4H), 2.64 (t, 4H), 1.93 (m, 2H). 13C NMR (75 MHz, DMSO) d 191.71 (C1), 151.07 (C10), 149.31 (C8), 137.98(C7), 136.56 (C2), 132.05 (C4), 130.82 (C5), 125.07 (C3), 124.04(C9), 119.01 (C6), 33.80 (C11), 30.12 (C12).
The chemical industry reduces the impact on the environment during synthesis,27148-03-4,Benzo[d]isothiazole-3(2H)-thione 1,1-dioxide,I believe this compound will play a more active role in future production and life.
Reference：
Article; Delgado, Fermin; Freire, Eleonora; Baggio, Ricardo; Gonzalez Pardo, Veronica; Dorn, Viviana; Dennehy, Mariana; Inorganica Chimica Acta; vol. 479; (2018); p. 266 – 274;,
Isothiazole – Wikipedia
Isothiazole – ScienceDirect.com