New Advances in Chemical Research in 2021, Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media. 18621-17-5, Name is 1-Benzhydrylazetidin-3-ol, molecular formula is C16H17NO, belongs to isothiazole compound. In a document, author is Clerici, F, introduce the new discover, Safety of 1-Benzhydrylazetidin-3-ol.
A series of isothiazole dioxides was synthesized and evaluated as inhibitors of protein farnesyltransferase from the parasite that causes African sleeping sickness (Trypanosoma brucei). The most potent compound in the series inhibited the parasite enzyme with an IC50 of 2 muM and blocked the growth of the bloodstream parasite in vitro with an ED50 of 10 muM. The same compound inhibited rat protein farnesyltransferase and protein geranylgeranyltransferase type I only at much higher concentration. (C) 2002 Elsevier Science Ltd. All rights reserved.
Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. If you are hungry for even more, make sure to check my other article about 18621-17-5, Safety of 1-Benzhydrylazetidin-3-ol.
Reference:
Isothiazole – Wikipedia,
,Isothiazole – ScienceDirect.com